ArticleProstate international2025
Use versus nonuse of antimicrobial prophylaxis prior to transperineal prostate biopsy: a propensity score-matched analysis.
Article in Prostate international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Predictors of false-positive results in men with Prostate Imaging-Reporting and Data System 4 lesions.Prostate international · 2026Article
- Multicenter Study on Integrating Prostate Magnetic Resonance Imaging with Prostate-Specific Antigen Density for Risk-Adapted Biopsy Strategy in a South Korean Cohort.Urology research & practice · 2026Article
- Antibiotic prophylaxis in ambulatory cystoscopy: Challenging its role even in high-risk patients-prospective observational study.Investigative and clinical urology · 2025Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Transperineal prostate biopsy offers advantage over a transrectal approach by reducing the risk of infectious complications. However, the necessity for antimicrobial prophylaxis (AP) before a transperineal prostate biopsy is less clear. This study aimed to study the rate of infectious complications following transperineal prostate biopsy with or without AP. Materials and methods: Propensity score matching was done for 1,273 patients who underwent transperineal prostate biopsy between October 2020 and October 2024 to adjust for differences in covariates. Parameters including the rate of urinary tract infection (UTI) requiring or not requiring hospitalization between patients who received AP and those who did not receive AP were then compared. Results: A total of 288 patients were matched for each group and baseline characteristics were balanced between groups. The overall incidence of UTI was very low in both groups without significant difference. UTI requiring hospitalization occurred in only one patient in the AP group (0.1%) and none in the non-AP group. Nonhospitalized UTI occurred in 0.7% of the AP group and 0.3% of the non-AP group ( Conclusion: There was no significant difference in the rate of UTI based on the use or nonuse of AP prior to transperineal prostate biopsy. The overall incidence of UTI was very low regardless of the use of AP. Omission of AP prior to transperineal prostate biopsy might be possible, which would help promote antimicrobial stewardship.
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