Evidence map›Paper›PMID 40620836›Full record

ArticleCureus2025

Near Miss Ruptured Ectopic Pregnancies: A Case Series of Diagnosis With Point-of-Care Ultrasound and an Independent Review of Radiology Images.

Jonathan Schonert, Joseph Minardi, Nicolas Denne, Justine Pagenhardt, Nicole Dorinzi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan SchonertEmergency Medicine, St. Luke's Hospital, Chesterfield, USA.
Joseph MinardiEmergency Medicine, West Virginia University, Morgantown, USA.
Nicolas DenneEmergency Medicine, West Virginia University School of Medicine, Morgantown, USA.
Justine PagenhardtEmergency Medicine, West Virginia University, Morgantown, USA.
Nicole DorinziEmergency Medicine, West Virginia University, Morgantown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

First-trimester pregnancy complications are common in the emergency department, with ectopic pregnancy being the leading cause of maternal mortality in this period. Emergency physicians play a critical role in early diagnosis and management, with proficiency in point-of-care ultrasound (POCUS) being an essential skill. Even when comprehensive radiology ultrasound is also available, independent image review remains crucial to ensure that subtle findings are not missed in this timely diagnosis. We present two cases of ruptured ectopic pregnancy initially evaluated in community emergency departments. Both cases involved lower abdominal pain, vaginal bleeding, and positive pregnancy tests. In each instance, transabdominal POCUS performed during initial evaluation identified concerning findings, including adnexal masses with complex echogenicity and pelvic free fluid. Despite comprehensive radiology ultrasound interpretations not confirming ectopic pregnancy, the emergency physician's reassessment of imaging raised concern for rupture, prompting urgent gynecologic intervention. Surgical exploration confirmed ruptured ectopic pregnancy in both cases, requiring operative management. Both patients had favorable postoperative outcomes. Ectopic pregnancy remains a high-risk condition necessitating thorough evaluation. These cases highlight the crucial role of POCUS and independent ultrasound interpretation by emergency physicians in preventing diagnostic delays. Recognizing subtle imaging findings, especially in cases where radiology interpretations are inconclusive, is critical for timely intervention. Emergency physicians should maintain a high index of suspicion and collaborate with gynecology and radiology colleagues to optimize patient outcomes.

Indexed as

case reportectopicfirst trimesterpocusvaginal bleeding

Identifiers

PMID40620836
PMCPMC12227135

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Registered trials

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