Evidence map›Paper›PMID 40620785›Full record

ArticleJournal of surgical case reports2025

A red flag and a red herring-dual pathology of isolated polycystic liver disease with underlying epithelioid angiosarcoma resulting in recurrent hepatic cyst haemorrhage.

Michael Yulong Wu, Juanita Noeline Chui, Cameron Gofton, Mahsa Ahadi, Kai Brown

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael Yulong WuDepartment of Gastroenterology and Hepatology, Royal North Shore Hospital, 1 Reserve Road, St Leonards, 2065, Sydney, Australia.ORCID https://orcid.org/0000-0003-1659-8599
Juanita Noeline ChuiFaculty of Medicine and Health, Northern Clinical School, University of Sydney, 1 Reserve Road, St Leonards, 2065, Sydney, Australia.ORCID https://orcid.org/0000-0001-9911-7863
Cameron GoftonDepartment of Gastroenterology and Hepatology, Royal North Shore Hospital, 1 Reserve Road, St Leonards, 2065, Sydney, Australia.
Mahsa AhadiDepartment of Anatomical Pathology, Royal North Shore Hospital, 1 Reserve Road, St Leonards, 2065, Sydney, Australia.
Kai BrownFaculty of Medicine and Health, Northern Clinical School, University of Sydney, 1 Reserve Road, St Leonards, 2065, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic liver disease (PLD) is an uncommon inherited condition that leads to progressive development of hepatic cysts that can become complicated by rupture, infection, and bleeding. We detail the case of a 53-year-old female presenting with haemoperitoneum secondary to hepatic cyst bleeding on a background of isolated polycystic liver disease. Despite extensive investigations to localize a bleeding source, repeated angioembolisation, and partial hepatic resection, the patient had recurrent hepatic haemorrhage. Posthumous histology of the resected liver revealed malignant epithelioid angiosarcoma, a rare vascular tumour underlying the PLD. This is the first reported case with a dual pathology of polycystic liver disease and primary liver epithelioid angiosarcoma. Infiltrative malignancies should be considered in atypical cases of recurrent hepatic haemorrhage.

Indexed as

epithelioid angiosarcomahepatic haemorrhageliver cystpolycystic liver disease

Identifiers

PMID40620785
PMCPMC12222048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.