Evidence map›Paper›PMID 40620664›Full record

ReviewClinical Medicine Insights. Oncology2025

Current Status of Cryoablation in Prostate Cancer Management.

Jakub Karwacki, Justyna Kiełbasa, Zuzanna Szczepaniak, Karol Zagórski, Maximilian Kobylański, Adam Gurwin, Patryk Patrzałek, Dawid Janczak, Wojciech Krajewski, Tomasz Szydełko and 1 more

Abstract readReview
In one paragraph

Review in Clinical Medicine Insights. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jakub KarwackiDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.ORCID https://orcid.org/0009-0005-4441-1877
Justyna KiełbasaDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.
Zuzanna SzczepaniakDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.
Karol ZagórskiDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.ORCID https://orcid.org/0009-0000-3809-3642
Maximilian KobylańskiDepartment of Urology, Regional Specialist Hospital, Wrocław, Poland.
Adam GurwinDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.
Patryk PatrzałekDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.
Dawid JanczakDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.
Wojciech KrajewskiDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.ORCID https://orcid.org/0000-0003-1727-2283
Tomasz SzydełkoUniversity Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.
Bartosz MałkiewiczDepartment of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology, Wroclaw Medical University, Wrocław, Poland.ORCID https://orcid.org/0000-0002-5933-3753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryoablation is gaining attention as a minimally invasive treatment option for prostate cancer (PCa), offering a balance between effective oncological control and preserving genitourinary functions and quality of life. Focal cryoablation is emerging as a viable option for patients with PCa, particularly those who prioritize functional outcomes such as erectile functions and urinary continence. Whole-gland cryoablation, on the contrary, may be more appropriate for intermediate- and high-risk PCa where complete ablation of the prostate is necessary to ensure oncological control. Despite promising results, there is considerable heterogeneity in the available data regarding the long-term oncological and functional outcomes of cryoablation techniques, making it premature to issue definitive treatment recommendations. Further studies, particularly randomized controlled trials, are needed to clarify the role of cryoablation in PCa treatment. This narrative review aims to present the most relevant and up-to-date evidence on both focal and whole-gland cryoablation in PCa, providing a comprehensive overview of their current clinical applications, outcomes, and future potential.

Indexed as

cryoablationcryosurgerycryotherapyfocal therapyfunctional preservationProstate cancerwhole-gland cryotherapy

Identifiers

PMID40620664
PMCPMC12227874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.