Evidence map›Paper›PMID 40620578›Full record

ArticleJournal of pain research2025

Efficacy and Central Mechanism of Acupuncture Treatment for Subacute Nonspecific Low Back Pain: A Clinical Neuroimaging Protocol.

Jia Ren, Zhen Gao, Bo-Ya Chang, Meng-Jie Cui, Hai-Jun Wang

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jia Ren *Second Clinical Medical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, 030619, People's Republic of China.
Zhen Gao *Second Clinical Medical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, 030619, People's Republic of China.ORCID 0000-0001-8410-8630
Bo-Ya ChangSecond Clinical Medical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, 030619, People's Republic of China.
Meng-Jie CuiSecond Clinical Medical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, 030619, People's Republic of China.ORCID 0009-0004-2416-5368
Hai-Jun WangSecond Clinical Medical College, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, 030619, People's Republic of China.ORCID 0000-0003-1930-6248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The chronification of pain is a multifaceted process, and low back pain (LBP), being one of the most prevalent health concerns globally, is particularly prone to developing into a chronic condition. Acupuncture is a common method of treating LBP in Chinese medicine, which is safe and effective. However, its mechanism of action is unclear, and more data are needed to support its application in LBP. Patients and Methods: This study is a randomized controlled neuroimaging trial, involving 120 subacute LBP patients assigned to the true acupuncture group, the sham acupuncture group, or the waiting list control group. The whole study period includes a 4-week treatment period and an 8-week follow-up period. The visual analog scale, Oswestry Disability Index, range of motion, and pressure pain threshold will be used to evaluate clinical efficacy, the short-form 36-item health survey and Pittsburgh Sleep Quality Index will be used to evaluate quality of life, the self-rating anxiety scale and self-rating depression scale will be used for assessing emotional state. The magnetic resonance imaging (MRI) scans will be performed to detect cerebral activity changes between the three groups of patients before and after treatment, as well as during follow-up periods. The clinical data and MRI data will be analyzed, respectively. Correlation analysis will be used to explore the correlation between neuroimaging data and clinical indicators. Conclusion: This study will provide rigorous evidence for the use of acupuncture to prevent the chronic progression of low back pain. Trial Registration: International Traditional Medicine Clinical Trial Registry ITMCTR2024000581, Registered on 17 October 2024.

Indexed as

acupuncturelow back painneuroimagingrandomized control trial

Identifiers

PMID40620578
PMCPMC12227004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.