ArticleAging brain2025
Frontal theta oscillations and cognitive flexibility: Age-related modulations in EEG activity.
Article in Aging brain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07141979 (Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of tDCS on Cognitive Flexibility and EEG Oscillations in Orthorexia Nervosa
Who cites it
5 citing papers in PubMed.
- Feasibility of Gamified EEG Neurofeedback Combined with Adaptive Working-Memory Training in Older Adults: A Pilot Study.Brain sciences · 2026Article
- Development and validation of the performance evaluation anxiety task: a computerized task to identify functionally significant test anxiety.Frontiers in psychology · 2026Article
- Representational dynamics during extinction of fear memories in the human brain.Nature human behaviour · 2026Article
- Age differences in electrocortical dynamics during uneven terrain walking.bioRxiv : the preprint server for biology · 2025Article
- Age differences in electrocortical dynamics during uneven terrain walking.Imaging neuroscience (Cambridge, Mass.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive flexibility, the ability to adapt one's behaviour in changing environments, declines during aging. Electroencephalography (EEG) studies have implicated midfrontal theta oscillations in attentional set-shifting, a measure of cognitive flexibility. Little is known about the electrocortical underpinnings of set-shifting in aging. Here, we investigated aging effects on set-shifting performance by analysing theta power in 20 young (mean age: 22.5 ± 2.9 years) and 19 older (mean age: 69.4 ± 6.1 years) adults. Increasing shift difficulty (i.e., intra- vs. extra-dimensional shifts) elicited worse performance in both age groups, with older adults showing overall longer reaction times (RTs) and increased RT variability. Young adults exhibited amplified midfrontal theta power increases with higher shift difficulty whereas older adults showed overall lower theta power and no task-related midfrontal theta power modulation, indicating potentially distinct underlying neural mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.