Evidence map›Paper›PMID 40620508›Full record

ArticleAging medicine (Milton (N.S.W))2025

Exploring Potentially Inappropriate Medication Use on Elderly Patients in a General Medicine Ward Using 2023 AGS Beers Criteria.

Subash Karki, Rahi Bikram Thapa, Rajeev Shrestha

Abstract read
In one paragraph

Article in Aging medicine (Milton (N.S.W)), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Subash KarkiDepartment of Pharmacy Purbanchal University School of Health Science Sundar Haraicha Gothgaun Nepal.ORCID https://orcid.org/0000-0002-4438-4291
Rahi Bikram ThapaDepartment of Pharmacy Purbanchal University School of Health Science Sundar Haraicha Gothgaun Nepal.ORCID https://orcid.org/0009-0002-2675-7856
Rajeev ShresthaNIHR Newcastle Patient Safety Research Collaboration Newcastle University Newcastle-upon-Tyne UK.ORCID https://orcid.org/0000-0003-1822-3969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Potentially inappropriate medication (PIM) use is a significant concern among the elderly, a vulnerable population, due to physiological changes, and the risk of multiple comorbidities and polypharmacy. This study aimed to assess the use of PIM among elderly inpatients in tertiary care hospital in eastern Nepal. Methods: A three-month prospective observational study was conducted, involving 200 eligible elderly patients admitted to general medicine ward. Relevant data were collected from patient case sheets, nursing and doctor cardex, discharge summaries, and via patient interviews. PIMs were identified based on the latest 2023 AGS Beers Criteria. Results: Among the 200 eligible patients, 108 (54.0%) were prescribed at least one PIM. Medications that should be avoided in older patients accounted for 32.2%, where prazosin and hyoscine were the most common. Additionally, 52.8% of the medications required cautious use, with diuretics being the most frequent one. Multivariate analysis revealed that patients with chronic kidney disease (CKD) and the number of prescribed medicines significantly influenced the likelihood of PIMs with an adjusted odd ratio of 6.730 (2.111-21.456) and 2.764 (1.448-5.276), respectively, at Conclusion: PIMs are more common among the elderly, with CKD and polypharmacy contributing significantly to their prevalence. To reduce PIM use, healthcare professionals, including clinical pharmacists, should implement targeted interventions, particularly for older adults with CKD who are managing with multiple medications.

Indexed as

AGS beers criteriaelderly patientsnepalpolypharmacypotentially inappropriate medications

Identifiers

PMID40620508
PMCPMC12226411

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.