ArticleFrontiers in medicine2025
Age as a key risk factor for deep vein thrombosis in patients with lower limb cellulitis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cellulitis of the lower extremities is a common bacterial skin infection that can lead to various complications, including deep vein thrombosis (DVT). Although previous studies have suggested an increased risk of thrombosis due to the pro-inflammatory state induced by cellulitis, the specific clinical characteristics and risk factors associated with DVT in cellulitis patients remain poorly understood. This study aims to identify the clinical characteristics and risk factors for DVT in patients with lower limb cellulitis. Methods: We conducted a 10-year retrospective study of patients treated for lower limb cellulitis at our institution between January 2013 and December 2023. Patients who underwent ultrasound examination to assess for DVT were included in the analysis. Clinical data were collected, including age, D-dimer levels, C-reactive protein (CRP) levels, body mass index (BMI), duration of antibiotic treatment, and relevant medical history (e.g., diabetes, malignancy, the use of corticosteroids, and immunosuppressive agents). Statistical analyses were performed to identify risk factors for thrombosis. Results: Among the patients included in the study, those who developed DVT were significantly older, with the majority being 70 years or older. No significant associations were found between thrombosis and other clinical parameters, including elevated CRP levels, D-dimer levels, BMI, or the duration of antibiotic treatment. Additionally, neither diabetes nor the use of corticosteroids or immunosuppressants showed a significant correlation with DVT development. Importantly, thrombosis occurred in both the affected and non-affected limbs, with no significant difference between them. Conclusion: Age, particularly being 70 years or older, was identified as an independent risk factor for the development of DVT in patients with lower limb cellulitis. These findings suggest that advanced age plays a critical role in DVT development in cellulitis patients, and further investigation is needed to explore the underlying mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.