Evidence map›Paper›PMID 40620391›Full record

ArticleGhana medical journal2025

A retrospective single-centre study on the histological profile of brain and spine tumours at a tertiary hospital in Ghana.

Mabel Banson, Felix Siaw-Debrah, Kwadwo Darko, Mawuli K Ametefe, Patrick Bankah

Abstract read
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Article in Ghana medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mabel BansonDepartment of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana.
Felix Siaw-DebrahDepartment of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana.
Kwadwo DarkoDepartment of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana.
Mawuli K AmetefeDepartment of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana.
Patrick BankahDepartment of Neurosurgery, Korle-Bu Teaching Hospital, Accra, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to describe the patient demographics, clinical presentation and histological subtypes of central nervous system (CNS) tumours in a tertiary facility. Design: Retrospective review of all the histopathological and medical records available for patients with tumours of the CNS operated on. Setting: Neurosurgical Unit, Department of Surgery, Korle-Bu Teaching Hospital. Participants: All adult and paediatric patients with histopathologically diagnosed CNS tumours. Main outcome measures: Frequency of histopathological subtypes of CNS tumours. Results: This study of 338 patients with CNS tumours showed a slight female predominance (183 females, 155 males). The mean age was 38.1 years. Brain tumours were more common (290 cases) than spinal tumours (48 cases), with symptoms like headaches (44.44%) and visual disturbance (24.31%) prevalent in brain cases, and paraparesis (35.42%) and low back pain (16.67%) in spinal cases. Certain symptoms were strongly indicative of specific tumour types, such as seizures (OR: 3.3, CI: 1.6 - 6.9, p = 0.005) with meningiomas and visual disturbances with sellar tumours (OR: 6.7, CI: 3.6 - 12.9, p<0.001). Most tumours were low-grade (78.69%). Meningiomas were the most common (33.14%), particularly meningothelial (38.39%). Gliomas, glioneuronal, and neuronal tumours were next in prevalence (28.40%), followed by sellar tumours (18.93%). Astrocytomas (60.42%) were the predominant glioma subtype. Conclusion: Low-grade tumours predominate in our setting. It is prudent that we channel efforts towards prompt diagnosis and treatment of such cases. Funding: None declared.

Indexed as

Brain NeoplasmsSpinal NeoplasmsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleGhanaHumansInfantMaleMeningiomaMiddle AgedRetrospective StudiesCentral Nervous System TumoursGliomaMeningiomaSub-Saharan Africa

Identifiers

PMID40620391
PMCPMC12224129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.