Evidence map›Paper›PMID 40620386›Full record

ArticleF&S reports2025

Observational cohort study exploring MediEmo smartphone application use, live birth, and in vitro fertilization treatment return rates.

Isla F Robertson, China R Harrison, Richard D Morey, Jacky Boivin, Ying Cheong

Abstract read
In one paragraph

Article in F&S reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isla F RobertsonUniversity of Southampton Faculty of Medicine, Human Development and Health, Princess Anne Hospital, Coxford Road, Southampton, United Kingdom.
China R HarrisonNational Institute for Health Research Applied Research Collaboration West (NIHR ARC West), Whitefriars, Lewins Mead, Bristol, United Kingdom.
Richard D MoreySchool of Psychology, College of Biomedical and Life Sciences, Cardiff University, Tower Building, Cardiff, United Kingdom.
Jacky BoivinWomen's Health Research Wales Centre and School of Psychology, College of Biomedical and Life Sciences, Cardiff University, Tower Building, Cardiff, United Kingdom.
Ying CheongUniversity of Southampton Faculty of Medicine, Human Development and Health, Princess Anne Hospital, Coxford Road, Southampton, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the associations between the use of the MediEmo smartphone application and in vitro fertilization (IVF) live birth and treatment return rates. Design: A 3-year observational cohort study. Subjects: Patients undergoing IVF were classified as users if they used the medication or emotion features of the MediEmo. Patients who did not use the two key features or declined to use the application were classified as nonusers. Exposure: The use of the MediEmo smartphone application. Main outcome measures: Outcomes of interest were the rate of live birth per fresh index cycle, live birth per complete cycle, and treatment return for a stimulated cycle of treatment within 12 months of the unsuccessful stimulated index cycle. Results: A total of 1,081 patients were eligible to use the MediEmo application, 863 were categorized as users and 218 as nonusers. MediEmo use was associated with a higher live birth rate per index cycle than nonusers (27.81% [n = 240/863] vs. 19.26% [n = 42/218], respectively, OR, 1.248; 95% CI, 1.041-1.509) and treatment return rate compared with nonusers (46.00% [n = 169/363] vs. 31.37% [n = 32/102], respectively, OR, 1.339; 95% CI, 1.092-1.656). It was not associated with the live birth rate per complete cycle. Conclusion: The observed positive association between MediEmo use and live birth and treatment return rates suggests benefits to patients and clinics. Further research and replication using a randomized controlled trial design are warranted, as is investment in the development of digital tools for use during IVF treatment.

Indexed as

live birth rateMediEmo usetreatment return rate

Identifiers

PMID40620386
PMCPMC12223561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.