Evidence map›Paper›PMID 40620330›Full record

ArticleSAGE open medicine2025

Primary versus secondary infertility: Epidemiology and characteristics from a referral hospital in Saudi Arabia.

Nouf A AlShamlan, Reem S AlOmar, Abdulrahman Abdulrazzaq Alfryyan, Abdulsalam Essam Almuhanna, AlJawhara Raed AlSaadoun, Halah Raaed AlMuhaidib, Mohammad Ghazi Alhaidari, Rakan Saud Alharbi, Abdullah H Alreedy, Nouf A AlTooq and 1 more

Abstract read
In one paragraph

Article in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nouf A AlShamlanDepartment of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID https://orcid.org/0000-0002-8049-237X
Reem S AlOmarDepartment of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID https://orcid.org/0000-0003-4899-7965
Abdulrahman Abdulrazzaq AlfryyanDepartment of Internal Medicine, King Fahd University Hospital, Dammam, Saudi Arabia.
Abdulsalam Essam AlmuhannaDepartment of Family Medicine, Alkhobar Health Network, Saudi Arabia.
AlJawhara Raed AlSaadounDepartment of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Halah Raaed AlMuhaidibDepartment of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mohammad Ghazi AlhaidariDepartment of Internal Medicine, Madinah Health Cluster, King Fahad Hospital, Saudi Arabia.
Rakan Saud AlharbiDepartment of Dermatology, Dammam Medical Complex, Saudi Arabia.
Abdullah H AlreedyDepartment of Family and Community Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Nouf A AlTooqDepartment of Obstetrics and Gynaecology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Amani S AlOtaibiDepartment of Obstetrics and Gynaecology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore the epidemiology and characteristics of primary versus secondary infertility cases referred to infertility clinics at a major Saudi Arabian referral hospital, as well as potential correlations between patients' characteristics and infertility types. Methods: All female patients who visited the infertility clinics between January 2020 and December 2022 were included in this retrospective chart review study. Data were collected on medical histories, medications, diagnostic tests, reproductive characteristics, and the type and cause of infertility. Results: During the study period, a total of 667 female patients attended the infertility clinic. The mean age was 33.64 ± 6.56 years. The mean marriage duration was 79.92 ± 57.17 months, and the mean duration of infertility was 59.80 ± 49.71 months. Of the total patients, 56.07% had secondary infertility, whereas 43.93% had primary infertility. The most frequently defined causes were unexplained, followed by combined factors. Temporal patterns show a gradual, but significant decrease in cases during the COVID-19 pandemic peak months (25.82% reduction between January and April). Results from diagnostic tests were generally normal for most patients. Females with secondary infertility tended to be older (Mean age = 34.64 vs 32.37 years) and had been married for longer (Mean duration 96.18 vs 68.86 months; Conclusion: Crucial information in the epidemiology of infertility has been found. The older age among secondary infertility, as well as the high proportion of unknown causes warrants further research. Women's health consultants and family physicians should initiate investigations and manage underlying causes during the waiting period for specialized clinic appointments.

Indexed as

epidemiologyfemale reproductive healthPrimary infertilitysecondary infertilitywomen health

Identifiers

PMID40620330
PMCPMC12227923

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.