Evidence map›Paper›PMID 40620285›Full record

ArticlePhysics and imaging in radiation oncology2025

A randomized safety study of tolerance to table rotation in dynamic trajectory radiotherapy in healthy volunteers.

Paul-Henry Mackeprang, Jenny Bertholet, Claas Wessels, Jean-Benoit Rossel, Andreas Limacher, Daniel M Aebersold, Michael K Fix, Peter Manser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul-Henry MackeprangDivision of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, 3010 Bern, Switzerland.
Jenny BertholetDivision of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, 3010 Bern, Switzerland.
Claas WesselsVarian Medical Systems Imaging Laboratory GmbH, 5405 Baden, Switzerland.
Jean-Benoit RosselDepartment of Clinical Research, University of Bern, 3012 Bern, Switzerland.
Andreas LimacherDepartment of Clinical Research, University of Bern, 3012 Bern, Switzerland.
Daniel M AebersoldDivision of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, 3010 Bern, Switzerland.
Michael K FixDivision of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, 3010 Bern, Switzerland.
Peter ManserDivision of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital and University of Bern, 3010 Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to show that table movement of dynamic trajectory radiotherapy (DTRT) does not induce more motion sickness than standard-of-care non-coplanar volumetric modulated arc therapy (ncVMAT). Forty-one healthy volunteers underwent dry-runs of DTRT and ncVMAT in four different, randomly allocated sequences. The primary outcome was the Motion Sickness Assessment Questionnaire (MSAQ) summary score. The average change in MSAQ summary score before to after dry-runs was 1.88 for DTRT and 1.62 for ncVMAT. The difference between both techniques was 0.26 [95% CI: -0.24 to 0.75]; the CI demonstrated non-inferiority of DTRT to ncVMAT for motion sickness in healthy volunteers.

Indexed as

DTRTDynamic trajectory radiotherapyMotion sicknessNon-coplanar radiotherapySafety studyVMAT

Identifiers

PMID40620285
PMCPMC12226396

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.