Evidence map›Paper›PMID 40620141›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2025

Premenstrual Dysphoric Disorder Prevalence and Symptoms Across Age Groups: A Cross-Sectional Study.

Adriana Orcesi Pedro, Roberto Carmignani Verdade, Maura Gonzaga Lapa, Juliana Dinéia Perez Brandão, Vivienne Carduz Castilho

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Article in BJOG : an international journal of obstetrics and gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Adriana Orcesi PedroDepartment of Gynecology and Obstetrics, Universidade Estadual de Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0003-0138-8935
Roberto Carmignani VerdadeDepartment of Gynecology and Obstetrics, Universidade Estadual de Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0002-8467-7267
Maura Gonzaga LapaLibbs Farmacêutica Ltda, Scientific Medical Division, São Paulo, Brazil.
Juliana Dinéia Perez BrandãoLibbs Farmacêutica Ltda, Scientific Medical Division, São Paulo, Brazil.
Vivienne Carduz CastilhoLibbs Farmacêutica Ltda, Scientific Medical Division, São Paulo, Brazil.

Funding

LIBBS Farmacêutica
6 · The paper itself

Abstract

objectiveTo estimate the prevalence and symptom severity of premenstrual dysphoric disorder (PMDD) in Brazilian women according to age groups, and to conduct an association analysis between psychoemotional and somatic symptoms.

designCross-sectional study.

setting303 private clinics across Brazil. POPULATION: 45 160 women aged 20-49 years.

methodsSelf-report questionnaire regarding the prevalence and intensity of premenstrual symptoms. Statistical analysis performed using Pearson's chi-square test and Poisson regression and multiple logistic regression.

main outcome measuresPrevalence and intensity of somatic and psychoemotional premenstrual symptoms.

resultsPrevalence of PMDD was 3.57% (95% CI: 3.40-3.75). Psychoemotional symptoms were more prevalent than somatic symptoms, with anxiety/tension (99.9%) and irritability/anger (99.8%) being the most frequently reported symptoms. Weight gain (92.5%) and edema (92.1%) were the most prevalent somatic symptoms. Anxiety/tension and headache occurred independently of other symptoms. Binge eating was associated with weight gain (OR = 2.77, 95% CI [2.11, 3.62]), acne (OR = 2.37, 95% CI [1.79, 3.10]), immunoallergic exacerbations (OR = 1.81, 95% CI [1.26, 2;60]) and edema (OR-0.74, 95% CI [0.55, 0.97]). Affective lability was associated with immunoallergic exacerbations (OR = 1.49, 95% CI [1.16, 1.91]) and mastalgia (OR = 1.29, 95% CI [1.02, 1.63]). Depression was associated with acne (OR = 0.72, 95% CI [0.57, 0.89]) and weight gain (OR = 0.77, 95% CI [0.61, 0.96]).

conclusionsThe prevalence of PMDD was consistent with other population studies. Psychoemotional symptoms were more prevalent. Association analysis provided new insights into premenstrual symptomatology.

Indexed as

Premenstrual Dysphoric DisorderAdultAge FactorsAnxietyBrazilCross-Sectional StudiesFemaleHumansMiddle AgedPrevalenceSeverity of Illness IndexSurveys and QuestionnairesYoung AdultBrazilian populationpremenstrual dysphoric disorderpsychoemotional symptomssomatic symptoms

Identifiers

PMID40620141
PMCPMC12411650

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.