Evidence map›Paper›PMID 40619700›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2025

Evaluating Postoperative Hidden Blood Loss in Proximal Femoral Nail Anti-Rotation Fixation: The Role of Greater Trochanter Fracture Comminution.

Hu Da, Shi-Ting Zhu, Guo-Dong Zhao, Qiao-Yun Xi

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Article in Medical science monitor : international medical journal of experimental and clinical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hu DaDepartment of Orthopedics, Lianshui People's Hospital of Kangda College Affiliated to Nanjing Medical University, Huai'an, Jiangsu, China.
Shi-Ting ZhuDepartment of Orthopedics, Lianshui People's Hospital of Kangda College Affiliated to Nanjing Medical University, Huai'an, Jiangsu, China.
Guo-Dong ZhaoDepartment of Orthopedics, Lianshui People's Hospital of Kangda College Affiliated to Nanjing Medical University, Huai'an, Jiangsu, China.
Qiao-Yun XiDepartment of Orthopedics, Lianshui People's Hospital of Kangda College Affiliated to Nanjing Medical University, Huai'an, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Intertrochanteric fractures can be managed using insertion of a proximal femoral nail anti-rotation (PFNA) intramedullary nail inserted into the femur. The helical blade used with the PFNA technique has the advantage of less bone removal and good biomechanical properties, but significant hidden blood loss (HBL) can occur. This study compared postoperative HBL in 219 elderly patients with intertrochanteric fractures using PFNA fixation, stratified by greater trochanter comminution status (comminuted vs non-comminuted). MATERIAL AND METHODS We retrospectively analyzed data on 219 elderly patients who underwent PFNA for intertrochanteric fractures between March 2019 and June 2024. The patients were divided into 2 groups: Group A (n=68) with comminuted fractures of the greater trochanter and Group B (n=151) with non-comminuted fractures. Demographic and clinical characteristics of patients were compared. Blood loss was calculated using established formulas. Intraoperative blood loss, postoperative HBL, postoperative complications, and length of hospital stay were statistically analyzed. RESULTS No significant differences were observed in demographic and clinical characteristics between the groups (P>0.05). However, Group A had significantly more intraoperative blood loss (70.0±24.1 ml vs 98.6±29.8 ml, P=0.000) and postoperative HBL (758.0±195.5 ml vs 1151.5±282.2 ml, P=0.000), and longer hospital stays (P=0.000), as well as higher rates of complications, including acute cerebral infarction, hemorrhagic shock, and heart failure (P values 0.015, 0.041, and 0.036, respectively). CONCLUSIONS Greater trochanter comminution is associated with significantly elevated HBL in intertrochanteric fractures treated with PFNA fixation. Orthopedic surgeons must recognize this risk factor in perioperative management.

Indexed as

Blood Loss, SurgicalFracture Fixation, IntramedullaryFractures, ComminutedHip FracturesPostoperative HemorrhageAgedAged, 80 and overBone NailsFemaleFemoral FracturesFemurHumansLength of StayMalePostoperative ComplicationsRetrospective Studies

Identifiers

PMID40619700
PMCPMC12247626

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.