Evidence map›Paper›PMID 40619599›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Boron Difluoride Formazanate Dye With Donor Planarization Engineering for 1060 nm Laser Activated Photothermal Theranostics.

Kang Xu, Mengchen Luo, Weili Wang, Tian Zhang, Yang Chen, Jinjun Shao, Peng Chen, Xiaochen Dong, Yu Cai

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kang XuState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.
Mengchen LuoState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.
Weili WangState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.
Tian ZhangState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.
Yang ChenState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.
Jinjun ShaoState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.
Peng ChenSchool of Chemistry, Chemical Engineering and Biotechnology, Institute for Digital Molecular Analytics and Science, Lee Kong Chian School of Medicine, Nanyang Technological University, 62 Nanyang Drive, Singapore, 637459, Singapore.
Xiaochen DongState Key Laboratory of Flexible Electronics (LoFE) & Institute of Advanced Materials (IAM), School of Flexible Electronics (Future Technologies), Nanjing Tech University, Nanjing, 211816, China.ORCID https://orcid.org/0000-0001-7327-8060
Yu CaiCenter for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310014, China.

Funding

National Natural Science Foundation of China 62120106002National Natural Science Foundation of China 62235007National Natural Science Foundation of China 62275119National Natural Science Foundation of China 62288102Natural Science Foundation of Jiangsu Province BZ2024040Research Innovation Plan for Graduate Students in Jiangsu Province KYCX24_1638
6 · The paper itself

Abstract

Phototheranostics within the second near-infrared (NIR-II, 1000-1700 nm) window offer considerable advantages compared to those operating in the visible and first near-infrared region (NIR-I, 700-900 nm). Herein, a donor-acceptor-donor (D-A-D) structured NIR-II absorbing Boron Difluoride Formazanate (BDF) dye FBDFDPA is developed through a donor engineering strategy for 1060 nm laser-excited photoacoustic imaging (PAI)-guided photothermal therapy (PTT). By replacing the donor unit from alkoxy-substituted triphenylamine with alkoxy-substituted diphenylamine, the planarity of the molecular conjugated skeleton is enhanced, thus promoting the intramolecular charge transfer (ICT) effect, leading to a 138 nm redshift in absorption and extending it into the NIR-II region. FBDFDPA NPs show excellent molar extinction coefficient (ε = 7.66 × 10

Indexed as

Boron CompoundsColoring AgentsPhotothermal TherapyTheranostic NanomedicineAnimalsCell Line, TumorHumansMiceNanoparticlesPhotoacoustic TechniquesBoron CompoundsColoring Agentsdonor engineeringNIR‐IIphotoacoustic imagingphotothermal therapy

Identifiers

PMID40619599
PMCPMC12499441

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.