ArticleParasitology research2025
Development and optimization of an ELISA method to detect Toxoplasma gondii oocyst infection in cats.
Article in Parasitology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Treatment of congenital toxoplasmosis with pyrimethamine combined with sulfadiazine in a Chinese neonate: a case report.Frontiers in pediatrics · 2026Article
- Bioinformatics-driven design and protective efficacy assessment of a multi-epitope vaccine forFrontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Toxoplasmosis caused by Toxoplasma gondii (T. gondii) is a zoonotic disease with great medical and veterinary significance. Felines, the definitive hosts of T. gondii, play a crucial role in the transmission of toxoplasmosis. The booming pet industry has led to more cats and cat-owning families, increasing the risk of toxoplasmosis transmission from animals to humans. Monitoring feline T. gondii infection accurately is crucial for reducing transmission risks. However, existing diagnostic methods focus on detecting whether cats are infected with T. gondii but fail to trace whether feline toxoplasmosis infections originate from oocysts or cysts. In this study, we assessed four late-stage development abundant proteins that were highly expressed specifically in sporulated oocysts to evaluate their specificity in binding to cat anti-T. gondii-oocyst serum. The LEA880 protein can only specifically react with cat anti-T. gondii-oocyst positive serum, but not with cat anti-T. gondii-cyst positive serum or negative cat serum. The optimized indirect enzyme-linked immunosorbent assay (iELISA) method based on the LEA880 protein exhibits good specificity and sensitivity in detecting T. gondii oocyst infection in cats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.