Evidence map›Paper›PMID 40619527›Full record

SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Clinical risk factors associated with cage migration after posterior approaches for lumbar interbody fusion: a 10-year systematic review and meta-analysis.

Haozhong Wang, Changming Xiao, Kaiquan Zhang, Mingzhong Xie, Sen Li

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haozhong WangDepartment of Orthopedic Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China.
Changming XiaoDepartment of Orthopedic Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China.
Kaiquan ZhangDepartment of Orthopedic Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China.
Mingzhong XieDepartment of Orthopedic Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China.
Sen LiDepartment of Orthopedic Surgery, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China. jht187@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCage migration (CR) after lumbar interbody fusion may result in intractable complications to patients. This meta-analysis was aimed to figure out risk factors of cage migration after posterior approaches for lumbar interbody fusion.

methodsLiterature was searched in the PubMed, Embase, Web of Science and Cochrane Library between Feb 2013 to Feb 2023. PRISMA guidelines were followed in this review. The keywords used in the search included: cage, retropulsion, migration, lumbar interbody fusion, spinal fusion. Odds ratio (OR) and 95% confidence interval (CI) of a potential risk factor was calculated via RevMan5.4.

results8 studies were finally included in this meta-analysis. 10 risk factors were assessed and the outcome showed that Screw loosening (OR 12.98, 95% CI 4.63 to 36.36, P < 0.01), endplate injury (OR 10.14, 95% CI 5.20 to 19.79, P < 0.01) and pear-shaped disc (OR 4.03, 95% CI 1.41 to 11.55, P < 0.01) were associated with cage migration, and poly-ether-ether-ketone (PEEK) cage (OR 0.51, 95% CI 0.27 to 0.96, P = 0.04) could reduce risk of cage migration.

conclusionScrew loosening, endplate injury and pear-shaped disc increased risk of CM after posterior approaches for lumbar interbody fusion, and PEEK cage probably reduce risk of postoperative cage migration.

Indexed as

Foreign-Body MigrationInternal FixatorsLumbar VertebraePostoperative ComplicationsSpinal FusionHumansProsthesis FailureRisk FactorsCage migrationCage retropulsionLumbar interbody fusionMeta-analysisRisk factors

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.