Evidence map›Paper›PMID 40619496›Full record

ArticleScientific reports2025

Survival days of patients with metastatic spinal tumors of lung cancer requiring surgery: a prospective multicenter study.

Takuya Takahashi, Takashi Hirai, Yuki Shiratani, Akinobu Suzuki, Kenichiro Kakutani, Satoshi Kato, Hiroyuki Tominaga, Hirokazu Inoue, Hirokatsu Sawada, Norihiko Takegami and 22 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Takuya TakahashiDepartment of Orthopedic Surgery, Institute of Science Tokyo, Tokyo, Japan.
Takashi HiraiDepartment of Orthopedic Surgery, Institute of Science Tokyo, Tokyo, Japan. hirai.orth@tmd.ac.jp.
Yuki ShirataniDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Akinobu SuzukiDepartment of Orthopaedic Surgery, Osaka Metropolitan University, Osaka, Japan.
Kenichiro KakutaniDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Satoshi KatoDepartment of Orthopaedic Surgery Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Hiroyuki TominagaDepartment of Orthopedic Surgery Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Hirokazu InoueRehabilitation Center, Jichi Medical University Hospital, Shimotsuke, Japan.
Hirokatsu SawadaDepartment of Orthopaedic Surgery, Nihon University School of Medicine, Tokyo, Japan.
Norihiko TakegamiDepartment of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Kazuo NakanishiDepartment of Orthopaedic Surgery, Kawasaki Medical School, Kurashiki, Japan.
Hideaki NakajimaDepartment of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan.
Masayuki IshiharaDepartment of Orthopaedic surgery, Kansai Medical University Hospital, Hirakata, Japan.
Tsutomu OshigiriDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
Toru FunayamaDepartment of Orthopaedic Surgery Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Takuya IimuraDepartment of Orthopaedic Surgery, Dokkyo Medical University, Mibu, Japan.
Shinji TanishimaDivision of Orthopedic Surgery, Department of Sensory and Motor Organs, School of Medicine, Faculty of Medicine, Tottori University, Yonago, Japan.
Hiroaki NakashimaDepartment of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Daisuke YamabeDepartment of Orthopaedic Surgery, Iwate Medical University, Morioka, Japan.
Ko HashimotoDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Koji UotaniDepartment of Orthopaedic Surgery, Okayama University Hospital, Okayama, Japan.
Masahiro FunabaDepartment of Orthopaedics Surgery, Yamaguchi University Graduate school of Medicine, Ube, Japan.
Narihito NagoshiDepartment of Orthopaedic Surgery, Keio University, Shinjuku, Japan.
Kazu KobayakawaDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Toshitaka YoshiiDepartment of Orthopedic Surgery, Institute of Science Tokyo, Tokyo, Japan.
Kazuyuki WatanabeDepartment of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
Toshio NakamaeDepartment of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Takashi KaitoDepartment of Orthopedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Gen InoueDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
Shiro ImagamaDepartment of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kota WatanabeDepartment of Orthopaedic Surgery, Keio University, Shinjuku, Japan.
Takeo FuruyaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgery for metastatic spinal tumors has improved postoperative activities of daily living. A few studies reported on prognostic factors assessed in large multicenter prospective studies for metastatic spinal tumors of lung cancer origin. This study aimed to determine preoperative prognostic factors in patients undergoing surgery for metastatic spinal tumors associated with lung cancer. This prospective registry study included 74 patients diagnosed and operated with metastatic spine tumors derived from lung cancer in 39 high-volume cancer centers. We examined the postoperative survival period and the preoperative factors related to postoperative survival time. We conducted univariate and multivariate Cox regression analyses to determine preoperative prognostic factors. The mean postoperative survival period was 343 days. Multivariate Cox regression analysis revealed a higher feeding score of vitality index, indications for molecularly targeted therapy, and a higher mobility score of Barthel index as independent factors associated with postoperative survival time in metastatic spinal tumors derived from lung cancer. Patients with indications for molecular-targeted therapy and good vitality exhibited longer survival. These results may help in surgical selection for patients with metastatic spinal tumors derived from lung cancer.

Indexed as

Lung NeoplasmsSpinal NeoplasmsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPrognosisProspective StudiesBarthel indexLung cancerMetastatic spinal tumorMolecularly targeted therapyPostoperative survival periodVitality index

Identifiers

PMID40619496
PMCPMC12230111

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