ArticleBMC nephrology2025
Prognostic value of the triglyceride-glucose index for continuous ambulatory peritoneal dialysis patients.
Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Time-updated explainable machine learning predicts short-term mortality in peritoneal dialysis patients.Renal failure · 2026Article
- Triglyceride-glucose index and the outcome of peritoneal dialysis patients: analysis of two cohorts.BMC nephrology · 2026Article
- Prognostic significance of the C-reactive protein-triglyceride-glucose index for all-cause and cardiovascular mortality in peritoneal dialysis: a multicenter cohort study.Scientific reports · 2025Article
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Authors and funding
6 authors.
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Abstract
objectiveWe are committed to demonstrating that the initial triglyceride-glucose (TyG) index possesses prognostic importance for patients undergoing continuous ambulatory peritoneal dialysis (CAPD).
methods354 patients who utilized continuous CAPD at Wuhan No.1 Hospital were recruited. The participants were classified into three unique groups according to the tertiles of the TyG index. The main endpoints were overall and cardiovascular (CVD) mortality, whereas the secondary outcomes were peritonitis, technical failure, and early-onset peritonitis. The association between the TyG index and outcomes utilizing Cox proportional hazard and restricted cubic spline analysis.
resultsOver a median follow-up of 72 months, 92 patients (26.0%) and 60 patients (16.9%) succumbed to all-cause and CVD mortality, respectively. The three groups exhibited significant differences for all-cause death (16.8% in tertile 1, 24.8% in tertile 2, and 36.4% in tertile 3). After full adjustment, patients with the highest TyG index demonstrated a significantly increased all-cause death relative to those in the lowest tertile (hazard ratio, HR, 2.31, 95% confidence interval, 95%CI 1.18-4.56, P = 0.015). Similarly, each unit increase in the TyG index was associated with a 1.32-fold elevated risk of all-cause death (HR 1.32, 95% CI 1.06-1.87, P = 0.031). Restricted cubic spline analysis indicated a relationship between the TyG index and all-cause mortality (P for nonlinearity > 0.05). Furthermore, the same findings were also seen with CVD mortality and secondary outcomes.
conclusionThe TyG index may function as a meaningful and reliable prognostic indicator in CAPD patients, suggesting its potential importance in improving risk stratification in clinical environments.
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