Evidence map›Paper›PMID 40619354›Full record

ArticleBMC women's health2025

Epidemiology of the global burden of atrial fibrillation among women of child-bearing age, 1990-2021: insights from the Global Burden of Disease Study 2021.

Shuwen Chen, Junpeng Xiong, Peiyang Zheng, Ronghui Yu

Abstract read
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Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Women's cardiovascular health in 2025:Saudi medical journal · 2026
    Review
  3. Article
  4. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shuwen Chen *Department of Cardiology, National Cardiovascular Disease Regional Center for Anhui, The First Affiliated Hospital of Anhui Medical University, 20 Wanshui Road, Hefei, Anhui, 230022, China.
Junpeng Xiong *Department of Cardiology, National Cardiovascular Disease Regional Center for Anhui, The First Affiliated Hospital of Anhui Medical University, 20 Wanshui Road, Hefei, Anhui, 230022, China.
Peiyang ZhengDepartment of Cardiology, National Cardiovascular Disease Regional Center for Anhui, The First Affiliated Hospital of Anhui Medical University, 20 Wanshui Road, Hefei, Anhui, 230022, China.
Ronghui YuDepartment of Cardiology, National Cardiovascular Disease Regional Center for Anhui, The First Affiliated Hospital of Anhui Medical University, 20 Wanshui Road, Hefei, Anhui, 230022, China. yuronghui1971@163.com.

Funding

Anhui Provincial Department of Science and Technology 202427b10020101
6 · The paper itself

Abstract

backgroundThis study aimed to analyze the global, regional, and national burden of atrial fibrillation (AF) in women of childbearing age (WCBA) from 1990 to 2021, to identify trends and disparities and to project the future burden of AF in population. METHODS AND

resultsData from the GBD 2021 were used to estimate the burden of AF in WCBA. Age-standardized rates (ASRs) of incidence, prevalence, disability-adjusted life years (DALYs), and mortality rate were calculated from 1990 to 2021. Joinpoint regression and Bayesian age-period-cohort analysis were applied to assess temporal trends, regional disparities, and to project future AF burden. From 1990 to 2021, the global number of AF cases in WCBA increased by 71,092 thousand, with increasing trends in incidence [estimated annual percentage change (EAPC = 0.99)], prevalence (EAPC = 1.23), DALYs (EAPC = 1.04) and mortality (EAPC = 0.69). The burden of AF was higher in high Socio-Demographic Index (SDI) areas than in low SDI areas, particularly in terms of ASPR per 100,000 (44.48 > 25.35), highlighting health inequalities. The burden of AF is particularly high in women over 40 years of age, peaking at 45–49 years of age, due to the accumulation of risk factors such as hypertension and body mass index. Projections suggest that the burden of AF will continue to increase globally, especially in low and medium SDI countries.

conclusionThe burden of AF in WCBA is increasing globally, with significant regional disparities. Effective public health interventions targeting key risk factors of hypertension and BMI. International cooperation and comprehensive health strategies are essential to reduce health inequities and improve AF prevention and management among WCBA.

Indexed as

Atrial FibrillationGlobal Burden of DiseaseGlobal HealthAdultDisability-Adjusted Life YearsFemaleHumansIncidenceMiddle AgedPrevalenceRisk FactorsYoung AdultAtrial fibrillation (AF)DeathsDisability-adjusted life years (DALYs)IncidenceWomen of childbearing age (WCBA)

Identifiers

PMID40619354
PMCPMC12232735

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.