Evidence map›Paper›PMID 40618343›Full record

ArticleAge and ageing2025

James Lind Alliance Priority Setting Partnership in co-existing dementia and hearing conditions: a research agenda defined by people with lived experience and healthcare professionals.

Eithne Heffernan, Sian Calvert, Tom Dening, Emma E Broome, Ruth Spriggs, Nahid Ahmad, Natalie Lerigo-Smith, Helen Henshaw

Abstract read
In one paragraph

Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eithne HeffernanNational Institute for Health and Care Research (NIHR), Nottingham Biomedical Research Centre, Nottingham, UK.
Sian CalvertNational Institute for Health and Care Research (NIHR), Nottingham Biomedical Research Centre, Nottingham, UK.
Tom DeningMental Health and Clinical Neurosciences, Faculty of Medicine and Health Sciences, School of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0003-3387-4241
Emma E BroomeNational Institute for Health and Care Research (NIHR), Nottingham Biomedical Research Centre, Nottingham, UK.
Ruth SpriggsNational Institute for Health and Care Research (NIHR), Nottingham Biomedical Research Centre, Nottingham, UK.
Nahid AhmadJames Lind Alliance, NIHR, Southampton, UK.
Natalie Lerigo-SmithNational Institute for Health and Care Research (NIHR), Nottingham Biomedical Research Centre, Nottingham, UK.
Helen HenshawNational Institute for Health and Care Research (NIHR), Nottingham Biomedical Research Centre, Nottingham, UK.ORCID 0000-0002-0547-4403

Funding

Alzheimer's Research UK ARUK-STRATEGY2022-002NIHR Nottingham Biomedical Research Centre NIHR203310NIHR Three Schools' Dementia Research Programme 102645/TSDRP/UNEB-ICDA-D03NIHR Three Schools' Dementia Research Programme 102645/TSDRP/UNEH-ICDA-D17RNID ISF23/57_HENSHAW
6 · The paper itself

Abstract

backgroundDementia and hearing conditions are both major public health concerns. Most people living with dementia also live with hearing conditions (e.g. hearing loss, tinnitus, vestibular disorders). Furthermore, hearing loss may be a risk factor for dementia. There is a critical need for research to explain the association between dementia and hearing conditions and to optimise assessments and treatments for this co-morbidity.

objectiveThis James Lind Alliance (JLA) Priority Setting Partnership (PSP) aimed to develop an agenda for research about dementia and hearing conditions by systematically identifying unanswered research questions that are prioritised by people living with these conditions and professionals from healthcare and social care.

methodsParticipants were people living with hearing conditions and/or dementia, supporters (e.g. carers, relatives), clinicians, and social care professionals. A survey (N = 404) gathered 47 research questions proposed by participants. An evidence-checking process confirmed that these questions were unanswered. A second survey (N = 560) produced a shortlist of 16 questions. At a final workshop (N = 19), the top 10 questions were prioritised.

resultsThe prioritised research questions spanned diverse topics, including training for clinicians about this co-morbidity, routine health checks that incorporate hearing and cognition, dementia risk reduction strategies for people living with hearing loss, and potential mechanisms underlying the link between hearing loss and dementia.

conclusionThis novel JLA PSP was the first to identify research priorities for two different, yet co-morbid, health conditions. It has important implications for researchers, funders, commissioners, and clinicians, particularly those working with older adults who have multiple long-term conditions.

Indexed as

Biomedical ResearchDementiaHealth PrioritiesHearing LossAgedComorbidityFemaleHealth PersonnelHumansMaleMiddle AgedRisk Factorsdementiahearing lossmild cognitive impairmentolder peopletinnitusvestibular disorders

Identifiers

PMID40618343
PMCPMC12229087

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.