ArticleDiscover oncology2025
Bibliometric and visualized analysis of mitophagy in liver cancer from 1998 to 2024.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundMitophagy is crucial for maintaining mitochondrial homeostasis and the internal environment of the liver. It plays a dual role in the emergence and progression of liver cancer by removing damaged mitochondria and supplying energy. Additionally, mitophagy can influence the effectiveness of liver cancer treatments through various signaling pathways.
aimThis study aims to summarize the research status, hot spots, frontiers, and development trends of mitophagy in liver cancer based on bibliometrics and visual analysis.
methodsPublications on mitophagy in liver cancer were searched in the Web of Science Core Collection (WoSCC) database as of December 11, 2024. Vosviewer, Co-Occurrence software, CiteSpace, and SCImago Graphica were utilized for bibliometric and visualized analysis.
resultsWe collected 703 publications from WoSCC. Over the past 27 years, the number of publications on mitophagy in liver cancer has shown a consistent upward trend. China leads in the number of publications and total citations. Notable institutions contributing significantly to this field include Zhejiang University, the Chinese Academy of Sciences, and Sun Yat-sen University. Key journals for publishing research on mitophagy in liver cancer are the International Journal of Molecular Sciences, Frontiers in Oncology, and Autophagy. Major contributors to this area of study include Wang Bin and Li Yan. In recent years, the mechanisms associated with mitophagy and liver cancer have remained a hot spot, including ferroptosis, aerobic glycolysis, transcription factor EB, mitochondrial dysfunction, and oxidative stress. In addition, combining sorafenib with melatonin may present a promising therapeutic option for advanced liver cancer.
conclusionThis is the first comprehensive and in-depth bibliometric study of trends and developments of mitophagy in liver cancer. It provides researchers with panoramic knowledge of this field, as well as research hotspots and future directions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.