Evidence map›Paper›PMID 40618254›Full record

ArticleNeural regeneration research2026

MicroRNAs in the pathogenesis of neurodegenerative disorders: Potential as therapeutic targets.

Aditi Singh, Manivannan Subramanian, Amit Singh

Abstract read
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aditi SinghDepartment of Biology, University of Dayton, Dayton, OH, USA.
Manivannan SubramanianDepartment of Biology, University of Dayton, Dayton, OH, USA.
Amit SinghDepartment of Biology, University of Dayton, Dayton, OH, USA.ORCID 0000-0002-2962-2255

Funding

Genetic Basis of Dorso-Ventral Patterning in the Drosophila EyeR01EY032959 · NEI · UNIVERSITY OF DAYTON · PI KANGO-SINGH, MADHURI, SINGH, AMIT · 2021 to 2025
$2.2M
NEI NIH HHS R01 EY032959
6 · The paper itself

Abstract

Neurodegenerative diseases (neurodegenerative disorders) are marked by the progressive degeneration of the structure and function of the central nervous system. They may result in the deterioration of cognitive, motor, and functional abilities. Diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis represent some of the most prominent examples of neurodegenerative disorders. Despite scientific advancement in understanding disease pathology and prognosis, the therapeutic strategies available for management remain limited. In recent years, microRNAs, small non-coding RNA molecules, have emerged as key players in the pathogenesis of neurodegenerative disorders. Therefore, understanding how these microRNAs affect disease pathology and pathway signaling is essential, and may open microRNAs as new avenues for potential therapeutic intervention. This review explores the role of microRNAs in various neurodegenerative diseases, discuss how microRNAs affect signaling pathways, and examine the potential of microRNAs as therapeutic targets.

Indexed as

Alzheimer’s diseaseamyotrophic lateral sclerosisgene expression regulationgeneticsHuntington’s diseasemicroRNAneurodegenerative diseasesParkinson’s disease

Identifiers

PMID40618254
PMCPMC13378811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.