ArticleJournal of breast cancer2025
Long-term Outcomes of Early Breast Cancer Stratified by Axillary Ultrasound Assessment.
Article in Journal of breast cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
7 authors.
Funding
Abstract
purposeDe-escalation of axillary lymph node (ALN) surgery in early breast cancer is increasingly common. This study aimed to identify patients suitable for this approach by comparing long-term survival based on preoperative axillary ultrasound (AUS).
methodsPatients undergoing surgery at Yonsei University Severance Hospital between January 2010 and December 2017 were categorized into "no suspicion" and "low suspicion" groups based on AUS findings.
resultsMedian follow-up duration was 92 months. The 10-year recurrence-free survival (RFS) and overall survival rates for the no suspicion and low suspicion groups were 94.2% and 90.1% (
conclusionThe low suspicion and fine-needle aspiration biopsy-negative group had poorer prognostic biomarkers, leading to differences in recurrence but not in overall survival. The preoperative ALN status did not affect survival rates. Even in patients with cT2 and low suspicion of ALN, the rate of three or more metastatic ALNs was low, suggesting that further axillary surgery may not be necessary if two or fewer metastatic lymph nodes are found in the sentinel lymph node.
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