Evidence map›Paper›PMID 40618182›Full record

ArticleThe international journal of medical robotics + computer assisted surgery : MRCAS2025

The Silent Transformation of Stereotactic Brain Biopsies After the Introduction of Robotics.

Eliane Weinbrenner, Mykola Gorbachuk, Kathrin Machetanz, Florian Grimm, Linda Oberle, Sophie S Wang, Marcos Tatagiba, Georgios Naros

Abstract read
In one paragraph

Article in The international journal of medical robotics + computer assisted surgery : MRCAS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Silent Transformation of Stereotactic Brain Biopsies After the Introduction of Robotics.The international journal of medical robotics + computer assisted surgery : MRCAS · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eliane WeinbrennerDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Mykola GorbachukDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Kathrin MachetanzDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.ORCID https://orcid.org/0000-0002-5350-4574
Florian GrimmDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Linda OberleDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Sophie S WangDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Marcos TatagibaDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.
Georgios NarosDepartment of Neurosurgery and Neurotechnology, Eberhard Karls University, Tuebingen, Germany.ORCID https://orcid.org/0000-0003-4807-6234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn frame-based stereotaxy, the design of the frame limits trajectory selection, e.g., to the temporal lobe and posterior fossa. We hypothesise that frame-less neuronavigation and robotic technology might have expanded these stereotactic corridors.

methodsWe analysed 376 frame-based, neuronavigated and robotic brain biopsies. We analysed entry (EP) and target (TP) point coordinates, trajectory lengths (TL) and angles (α

resultsRobotics liberated TP and EP selection, enabling trajectories not applicable with the frame. There was an increased application of lateral trajectories (reducing α1) while decreasing TL. There was a significant STS reduction attributable to a modification of the surgical approach (twist drill vs. burr hole).

conclusionsRobotics modified trajectory selection and the surgical approach. Duration and invasiveness of brain biopsies were decreased without affecting diagnostic yield or morbidity. This may represent a clinical benefit of robotics compared with frame-based and frame-less stereotaxy.

Indexed as

BrainRoboticsRobotic Surgical ProceduresStereotaxic TechniquesAdultAgedBiopsyFemaleHumansMaleMiddle AgedNeuronavigationbrain biopsyframe‐less stereotactic surgeryrobot‐assisted surgeryroboticsstereotaxy

Identifiers

PMID40618182
PMCPMC12228906

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.