ArticleJournal of health, population, and nutrition2025
Association between energy-adjusted dietary inflammatory index and sleep quality disorders: a cross-sectional study on fasa adult cohort.
Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association between opium consumption and sarcopenia in middle-aged and older adults: findings from the Fasa Adults Cohort Study (FACS).Scientific reports · 2026Article
- Dietary diversity and its associations with sleep quality and chronotype in young and middle-aged adults.Frontiers in nutrition · 2025Article
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Authors and funding
12 authors.
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Abstract
backgroundThe cross-link between diet, sleep quality, and chronic inflammation is increasingly recognized and gaining significant attention. However, current research on this topic is limited and conflicting. In this study, we explore the connection between diet's inflammatory potential, measured by the Energy-Adjusted Dietary Inflammatory Index (E-DII), and sleep disorders in a rural Iranian population. Our hypothesis suggests that an inflammatory diet may contribute to sleep quality disorders.
methodsThis cross-sectional study included data from the Fasa Adult Cohort Study (FACS) (n = 10,138). Sleep efficiency < 85%, sleep duration < 7 h, and sleep latency > 15 min were defined using the Pittsburgh Sleep Quality Index (PSQI). The E-DII was calculated using a validated 125-item food frequency questionnaire. Multivariable logistic regression models assessed the association between E-DII quartiles and sleep disorders.
resultsOur analyses included 9,761 individuals with a mean age of 49 ± 10 years. The average E-DII was - 0.30 ± 2.05. After adjusting for several confounders, participants in the highest quartile of E-DII had significantly higher odds of experiencing high sleep latency (OR = 1.30, 95%CI: 1.11-1.51, p-value < 0.001), low sleep efficiency (OR = 1.43, 95%CI: 1.17-1.76, p-value < 0.001), using sleeping pills (OR = 1.53, 95%CI: 1.19-1.97, p-value < 0.001), and no leg restlessness (OR = 0.83, 95%CI: 0.71-0.97, p-value 0.02) compared to those in the lowest quartile. However, E-DII did not correlate with sleep duration or daily dozing-offs.
conclusionOur findings have implications for dietary interventions in managing sleep disorders. Individuals with sleep difficulties, particularly in initiating sleep, are advised to reduce intake of proinflammatory nutrients and increase consumption of anti-inflammatory nutrients.
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