Evidence map›Paper›PMID 40618133›Full record

ArticleBMC public health2025

Prevalence and patterns of multiple long-term conditions among lymphatic filariasis patients in Odisha, India: a community-based cross-sectional study.

Abhinav Sinha, Prakash Kumar Sahoo, Krushna Chandra Sahoo, Patrick Highton, Shubhashisha Mohanty, Trupti Nayak, Akshya Kumar Prusty, Sujata Choudhury, Barsha Kumari, Karl Puchner and 2 more

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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Abhinav SinhaICMR-Regional Medical Research Centre, Bhubaneswar, India.
Prakash Kumar SahooICMR-Regional Medical Research Centre, Bhubaneswar, India. shuvaprakash@gmail.com.
Krushna Chandra SahooICMR-Regional Medical Research Centre, Bhubaneswar, India.
Patrick HightonDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK.
Shubhashisha MohantyDirectorate of Public Health, National Vector Borne Disease Control Programme, Government of Odisha, Bhubaneswar, India.
Trupti NayakDirectorate of Public Health, National Vector Borne Disease Control Programme, Government of Odisha, Bhubaneswar, India.
Akshya Kumar PrustyRegional Research Institute of Homeopathy, Puri, India.
Sujata ChoudhuryRegional Research Institute of Homeopathy, Puri, India.
Barsha KumariSouth Asian Institute of Health Promotion, Bhubaneswar, India.
Karl PuchnerLaboratory of Primary Health Care, General Medicine and Health Services Research, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Kamlesh KhuntiDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, LE5 4PW, UK.
Sanghamitra PatiICMR-Regional Medical Research Centre, Bhubaneswar, India. drsanghamitra12@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeglected tropical diseases (NTDs), such as lymphatic filariasis, mimic other chronic conditions and share common risk behaviors with parallel health system issues that require unique interventions. Multiple long-term conditions (MLTCs or multimorbidity), defined as two or more chronic conditions has become increasingly common in low- and middle-income countries (LMICs) such as India. However, data on the prevalence of the interface between NTDs and other chronic conditions are lacking. We estimated the prevalence and correlates of MLTC, assessed the commonly occurring patterns, and investigated the association between self-rated health (SRH) and the number of chronic conditions among patients with lymphatic filariasis.

methodsA cross-sectional study was conducted in Odisha, India, using a prevalidated MLTC assessment tool. We employed systematic random sampling to recruit 584 participants aged ≥ 18 years having lymphatic filariasis. MLTC was defined as the coexistence of one or more chronic conditions along with lymphatic filariasis. A multivariable logistic regression model was used to identify the correlates presented as adjusted odds ratios (AORs) with 95% confidence intervals (CIs). A hierarchical cluster analysis was conducted to identify the major clusters of chronic conditions. An ordinal regression model was used to assess the association between SRH and the number of chronic conditions.

resultsThe overall prevalence of MLTC was 68.8% (95% CI: 64.9-72.6), while the mean number of chronic conditions was 2 ± 2.3. The chance of having MLTCs was greater among males [AOR: 3.9 (95% CI: 2.1-7.3)] than females. Participants with education at the primary and secondary school levels had greater odds of having MLTC [AOR: 2.2 (95% CI: 1.3-3.7)] and [AOR: 2.3 (95% CI: 1.3-3.8)], respectively. The commonly observed triad was lymphatic filariasis with arthritis and peptic ulcer disease (1.5%), while the most common tetrad was lymphatic filariasis, hypertension, diabetes and peptic ulcer disease (0.7%). There was a per unit decrease in SRH with each additional chronic condition.

conclusionWe observed a high prevalence of MLTC among people with lymphatic filariasis. The findings of this study will not only be useful for both resource and planning in India but also in similar LMICs with a high burden of lymphatic filariasis.

Indexed as

Elephantiasis, FilarialMultimorbidityAdolescentAdultAgedChronic DiseaseCross-Sectional StudiesFemaleHumansIndiaMaleMiddle AgedPrevalenceYoung AdultChronic conditionsIndiaLymphatic filariasisMultimorbidityMultiple long-term conditionsNeglected tropical diseases

Identifiers

PMID40618133
PMCPMC12228321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.