Evidence map›Paper›PMID 40618050›Full record

ArticleBMC gastroenterology2025

Endoscopic characteristics and treatment modalities of gastrointestinal glomus tumors: a multicenter retrospective study.

Yu-Qing Gong, Hai-Xing Wang, Lin Han, Yi-Sen Huang, Yi Ding, Jin-Yan Zhang, Zhong Xu, Wei-Feng Huang

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Qing GongDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Hai-Xing WangEndoscopy Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Lin HanDepartment of Gastroenterology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, 363000, China.
Yi-Sen HuangDepartment of Gastroenterology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, 362002, China.
Yi DingDepartment of Pathology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Jin-Yan ZhangDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Zhong XuDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Wei-Feng HuangDepartment of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China. hwf0625@xmu.edu.cn.ORCID http://orcid.org/0000-0002-9755-7299

Funding

Investigator-Initiated Clinical Research Fund Project of The First Affiliated Hospital of Xiamen University XMFHIIT-2023SL060Natural Science Foundation of Fujian Province 2023J011616
6 · The paper itself

Abstract

backgroundGlomus tumors are rare mesenchymal neoplasms originating from glomus cells, most commonly occurring in the distal extremities, with rare occurrences in the gastrointestinal tract. This study aims to retrospectively analyze the endoscopic features and treatment modalities of gastrointestinal glomus tumor.

methodsThis retrospective study analyzed data from 12 patients of gastrointestinal glomus tumor diagnosed between January 2010 and October 2024 across three large tertiary hospitals in China. Collected data included demographic characteristics, endoscopic findings, endoscopic ultrasound (EUS) features, pathological and immunohistochemical profiles, treatment methods, and prognosis.

resultsA total of 12 patients were included, 10 of whom were female, with a mean age of 48.33 ± 9.22 years. The mean tumor size was 2.54 ± 1.13 cm, with most tumors located in the antrum and body of the stomach. Endoscopic examination revealed nonspecific submucosal protrusions, sometimes accompanied by erythema or ulcers on the surface. EUS revealed the tumors usually originated from the submucosa and/or muscularis propria, presenting as well-defined, round, hypoechoic nodules with homogeneous internal echoes. Eight patients with smaller lesion diameters received endoscopic resection, while four underwent surgical resection. The mean postoperative hospital stay was significantly shorter in the endoscopic group (6.00 ± 1.83 days) compared to the surgical group (11.50 ± 4.20 days, P < 0.05). Endoscopic follow-up showed no recurrence in any patient.

conclusionGastrointestinal glomus tumors most commonly occur in the stomach. Endoscopic examination revealed nonspecific submucosal protrusions. Both surgical and endoscopic resections are effective treatment options, with endoscopic resection offering advantages in terms of shorter hospital stays.

Indexed as

Endoscopy, GastrointestinalGastrointestinal NeoplasmsGlomus TumorAdultChinaEndosonographyFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesEndoscopic ultrasoundEndoscopyGastrointestinal tractGlomus tumorTreatment

Identifiers

PMID40618050
PMCPMC12228251

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