SynthesisBMC cancer2025
Effect of different types of aerobic exercises on cancer-related fatigue among colorectal cancer patients: a meta-analysis based on randomized controlled trials.
Synthesis in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Clinical Significance and Potential Molecular Mechanisms of Angiotensin-Converting Enzyme 2 in Colorectal Cancer.World journal of oncology · 2026Article
- Patient-reported Symptoms Differ Between Patients With Brain Metastasis Starting Either Focal Stereotactic Radiotherapy or Whole-brain Radiotherapy.Cancer diagnosis & prognosisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColorectal cancer (CRC) is a prevalent and lethal disease. Cancer-related fatigue (CRF) poses a significant challenge to patients during their daily life and rehabilitation. Research indicates that aerobic exercises can alleviate CRF, but the optimal type, intensity, and timing of exercise interventions remain unclear.
aimTo conduct a meta-analysis of randomised control trials comparing the effects of different aerobic exercise intensities and training protocols on CRF and HRQoL.
methodThis meta-analysis searched electronic databases, including PubMed, Web of Science, Embase, and Cochrane Library, from their inception until February 2024. The meta-analyses were conducted using Revman 5.3 software. It examined the effects of different types of aerobic exercises on CRF among CRC patients.
resultsUltimately, 9 studies were included with a total of 425 patients. The meta-analysis results showed that aerobic exercises significantly reduce symptoms of CRF (SMD = - 0.35, Z = 2.39, P = 0.02), with continuous and interval training presenting the most promising type. The intensity and type of exercise influence CRF outcomes. The analysis also revealed potential publication bias in CRF research, suggesting the need for more studies that include negative results.
conclusionThese findings underscore the importance of personalized exercise prescriptions and integrating exercise into cancer care to improve CRF and enhance patients' quality of life. Further research is necessary to explore the best exercise regimens and their long-term effects.
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