Evidence map›Paper›PMID 40618007›Full record

SynthesisPediatric cardiology2026

Fontan Patients with a Systemic Left Ventricle Have Greater Exercise Capacity than those with a Systemic Right Ventricle: A Systematic Review and Meta-Analysis.

Dustin M Anderson-Bell, Edward H Hardison, Muhammed Rashid, Benjamin H Hammond, Matthew Hegewald, Tanner E Rapp, Michelle Ploutz, Richard V Williams, Daniel Ziebell, Nathorn Chaiyakunapruk

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dustin M Anderson-Bell *Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA. dustin.anderson-bell@hsc.utah.edu.ORCID http://orcid.org/0000-0002-3495-7033
Edward H Hardison *Department of Pediatric Cardiology, Primary Children's Hospital and University of Utah, 81 N Mario Capecchi Drive, Salt Lake City, UT, 84113, USA. nedhardison@gmail.com.ORCID http://orcid.org/0000-0003-2947-7745
Muhammed RashidDepartment of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.
Benjamin H HammondDepartment of Pediatric Cardiology, Primary Children's Hospital and University of Utah, 81 N Mario Capecchi Drive, Salt Lake City, UT, 84113, USA.
Matthew HegewaldDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Intermountain Medical Center, Murray, UT, USA.
Tanner E RappDivision of Public Health, University of Utah, Salt Lake City, UT, USA.
Michelle PloutzDepartment of Pediatric Cardiology, Primary Children's Hospital and University of Utah, 81 N Mario Capecchi Drive, Salt Lake City, UT, 84113, USA.
Richard V WilliamsDepartment of Pediatric Cardiology, Primary Children's Hospital and University of Utah, 81 N Mario Capecchi Drive, Salt Lake City, UT, 84113, USA.
Daniel ZiebellDepartment of Pediatric Cardiology, Primary Children's Hospital and University of Utah, 81 N Mario Capecchi Drive, Salt Lake City, UT, 84113, USA.
Nathorn ChaiyakunaprukDepartment of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.

Funding

CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
NIH HHS UM1TR004409
6 · The paper itself

Abstract

Cardiopulmonary exercise testing (CPET) is a useful metric to track the functional capacity and prognosis in patients with Fontan circulation. Systemic ventricular morphology may influence CPET interpretation. This systematic review and meta-analysis assessed the impact of systemic ventricular morphology on CPET outcomes. PubMed, Embase, and Cochrane were searched from inception through December 2024. Inclusion criteria were (1) Fontan circulation, (2) CPET via treadmill or cycle ergometer, and (3) outcomes stratified by systemic ventricle. Extracted outcomes included peak VO

Indexed as

Exercise ToleranceFontan ProcedureHeart Defects, CongenitalHeart VentriclesExercise TestHumansOxygen ConsumptionCardiopulmonary exercise testingCongenital heart diseaseFontan circulationMeta-analysisSingle ventricleSystematic reviewSystemic ventricular morphology

Identifiers

PMID40618007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.