Evidence map›Paper›PMID 40617989›Full record

ArticleOdontology2026

Effect of radiotherapy on the biomechanical preparation of different instrumentation kinematics.

Gunther Ricardo Bertolini, Tamara Justiniano Cronenbold, Heitor Silva Prado, Helena Cristina de-Assis, Jardel Francisco Mazzi-Chaves, Alexandra Mussolino de Queiroz, Harley Francisco de Oliveira, Aline Evangelista de Souza Gabriel, Manoel Damião Sousa-Neto, Fabiane Carneiro Lopes-Olhê

Abstract read
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In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Damage of irradiated teeth by ultrasonic scaling: an in vitro study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gunther Ricardo BertoliniDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0002-6386-1452
Tamara Justiniano CronenboldDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0003-2635-2621
Heitor Silva PradoDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0003-2092-3403
Helena Cristina de-AssisDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0001-7492-0385
Jardel Francisco Mazzi-ChavesDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0002-9889-1790
Alexandra Mussolino de QueirozDepartment of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0003-2900-5000
Harley Francisco de OliveiraDepartment of Internal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0002-7408-5137
Aline Evangelista de Souza GabrielDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0002-9280-2945
Manoel Damião Sousa-NetoDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil.ORCID http://orcid.org/0000-0002-7696-7600
Fabiane Carneiro Lopes-OlhêDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Av. Do Café, s/n, Ribeirão Preto, São Paulo, 14020-904, Brazil. fabiane.lopes@usp.br.ORCID http://orcid.org/0000-0003-4375-3371

Funding

CAPES 33002029032P4
6 · The paper itself

Abstract

To evaluate the effect of biomechanical preparation on irradiated root dentin after the use of different endodontic instrumentation techniques. Sixty mandibular canines were randomly assigned to two groups: non-irradiated (30 canines) and irradiated (30 canines subjected to 30 cycles of 2 Gy, totaling 60 Gy). After radiotherapy, the samples were scanned using micro-CT to assess the 3D morphology of the root canal and to calculate the length, thickness, volume, surface area and transport of the canal. The groups were redistributed into 3 subgroups (n = 10) according to the instrumentation protocol: GI-manual M-easy Ni-Ti file up to #50.05; GII-rotary instrument ProTaper Next up to #50/.06; GIII-reciprocating instrument Reciproc #R50. After instrumentation, the specimens were scanned again in micro-CT following the same parameters as the initial acquisition. Statistical analysis was performed using two-factor analysis of variance (ANOVA) test with Tukey's post-test considering the variables "instrumentation protocol" and "radiotherapy". The three-factor ANOVA test with Tukey's post-test was carried out to compare the influence of radiotherapy, instrumentation and root thirds (cervical, middle and apical) on root canal transportation data. Irradiated teeth showed a greater increase in surface area and percentage of walls touched, while for root canal transport and volume, differences were observed only in relation to the type of preparation, in ascending order for the manual, rotary and reciprocating systems. Descriptive analysis showed that altered thickness in the middle-apical thirds occurred mainly in teeth irradiated with rotary and reciprocating instrumentation protocols. Irradiation of teeth can affect biomechanical preparation parameters of different instrument kinematics used to prepare canine root canals.

Indexed as

Dental Pulp CavityDentinRoot Canal PreparationBiomechanical PhenomenaCuspidHumansIn Vitro TechniquesX-Ray MicrotomographyComputed microtomographyDentinEndodonticsRadiotherapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.