Evidence map›Paper›PMID 40617962›Full record

ReviewNpj viruses2025

Highly pathogenic avian influenza H5N1 in the United States: recent incursions and spillover to cattle.

Ahmed Mostafa, Aitor Nogales, Luis Martinez-Sobrido

Abstract readReview
In one paragraph

Review in Npj viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  9. Influenza.Nature reviews. Disease primers · 2026
    Review
  10. Article
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  13. Review
  14. Article
  15. Article
  16. Lack of respiratory droplet transmission of two recent human influenza A(H5N1) viruses in female ferrets.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed MostafaHost-pathogen interactions (HPI) and Disease Intervention and Prevention (DIP) programs, Texas Biomedical Research Institute, San Antonio, TX, USA. aelsayed@txbiomed.org.
Aitor NogalesCenter for Animal Health Research, CISA-INIA-CSIC, Madrid, Spain.
Luis Martinez-SobridoHost-pathogen interactions (HPI) and Disease Intervention and Prevention (DIP) programs, Texas Biomedical Research Institute, San Antonio, TX, USA. lmartinez@txbiomed.org.

Funding

Dynamics of the protective vaccine-induced human influenza neuraminidase B cell responseR01AI145332 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KOBIE, JAMES J, MARTINEZ-SOBRIDO, LUIS · 2019 to 2022
$3.0M
Center for Research on Influenza Pathogenesis and Transmission (CRIPT),NIH/NIAID contract # 75N93021C00014NIAID NIH HHS R01 AI145332Texas Biomed Forum Award # 1520001
6 · The paper itself

Abstract

Since Spring 2024, new genotypes of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b have been identified in the United States (US). These HPAI H5N1 genotypes have caused unprecedented multi-state outbreaks in poultry and dairy farms, and human infections. Here, we discuss the current situation of this outbreak and emphasizes the need for pre-pandemic preparedness to control HPAI H5N1 in both poultry and dairy farms in the US.

Identifiers

PMID40617962
PMCPMC12228781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.