Evidence map›Paper›PMID 40616899›Full record

ReviewCurrent opinion in biotechnology2025

Harnessing the potential of microbial methane utilization for chasing sustainability.

Marina G Kalyuzhnaya, Jin Wang, Amy C Rosenzweig

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marina G KalyuzhnayaDepartment of Biology, San Diego State University, San Diego, CA 92182, USA. Electronic address: mkalyuzhnaya@sdsu.edu.
Jin WangDepartment of Chemical Engineering, Auburn University, Auburn, AL 36849, USA. Electronic address: wang@auburn.edu.
Amy C RosenzweigDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, IL 60208, USA. Electronic address: amyr@northwestern.edu.

Funding

Metalloenzymes and metal homeostasisR35GM118035 · NIGMS · NORTHWESTERN UNIVERSITY · PI AMY C. ROSENZWEIG · 2016 to 2026
$7.1M
NIGMS NIH HHS R35 GM118035
6 · The paper itself

Abstract

Microbial methane utilization (known as methanotrophy) serves as a gatekeeper of methane emissions in numerous ecosystems. Methanotrophy became a platform for the production of biofuels, value-added chemicals, and novel molecules from natural or renewable gas. Methanotroph- driven Methanotroph-driven processes enable novel solutions for bioremediation, biomining of minerals, methane mitigation, and agriculture. All applications rely on in-depth understanding of methanotroph biochemistry, genetics, physiology, and ecological fitness. Here, we review recent advances in the enzymology of methane utilization and methanotroph carbon assimilation pathways as well as progress toward engineering both native and synthetic methanotrophs. New bioreactor approaches to overcoming methane and oxygen mass transfer limitations are also described. Continued research in these areas is critical to future success in methanotroph optimization for industrial processes.

Indexed as

MethaneBiodegradation, EnvironmentalBiofuelsBioreactorsBiofuelsMethane

Identifiers

PMID40616899
PMCPMC12359086

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.