Evidence map›Paper›PMID 40616675›Full record

ArticleParasitology research2025

Chemical characterization and bioactivity of cigarette butt extract as oviposition deterrent and larvicide against Aedes aegypti.

Rana Zain Khizar, Farrukh Baig, Unsar Naeem-Ullah, Naeem Iqbal, Abid Hussain

Abstract read
In one paragraph

Article in Parasitology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Antidiabetic potential ofJournal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rana Zain KhizarInstitute of Plant Protection, Muhammad Nawaz Shareef University of Agriculture, Multan, Pakistan.
Farrukh BaigInstitute of Plant Protection, Muhammad Nawaz Shareef University of Agriculture, Multan, Pakistan. farrukh.baig@mnsuam.edu.pk.
Unsar Naeem-UllahInstitute of Plant Protection, Muhammad Nawaz Shareef University of Agriculture, Multan, Pakistan.
Naeem IqbalInstitute of Plant Protection, Muhammad Nawaz Shareef University of Agriculture, Multan, Pakistan.
Abid HussainDepartment of Soil and Environmental Sciences, Muhammad Nawaz Shareef University of Agriculture, Multan, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aedes aegypti, the primary vector of viruses such as dengue, chikungunya, and yellow fever, poses a global health challenge. Traditional vector control strategies predominantly rely on broad-spectrum insecticides, which not only contribute to development of resistance in mosquitoes but also pose significant risks to non-target organisms and the environment. Here, we assessed the potential of cigarette butt (CB) extract for the management of A. aegypti population. Globally, 4.5 trillion CBs are being wasted annually, which is expected to rise to nine trillion by 2025. So, repurposing this waste for vector control offers an innovative approach. This study evaluated the potential of CB extract to deter ovipositing females and to assess larval mortality of A. aegypti using three concentrations of CB extract (1 CB, 2 CBs, and 3 CBs) against a control (water only). Our results revealed that highest concentration (3 CBs) significantly repelled the egg-laying females and resulted in 100% mortality of younger mosquito larvae (1st and 2nd instars) within 24 h of exposure, whereas complete mortality in mature larvae (3rd and 4th instars) was observed within 48 h of exposure. GC-MS analysis of CB extracts, using acetone and methanol as solvents, revealed both qualitative and quantitative differences in the chemical composition. Identified compounds include nicotine, phthalic acid, terephthalic acid, and acetonyl dimethyl carbinol. This study presents an innovative solution for recycling cigarette butt waste to control A. aegypti population at both adult and larval stages and highlights the potential to utilize CB waste into integrated vector management programs.

Indexed as

AedesInsecticidesInsect RepellentsOvipositionPlant ExtractsAnimalsFemaleGas Chromatography-Mass SpectrometryLarvaMosquito ControlMosquito VectorsTobacco ProductsInsecticidesInsect RepellentsPlant ExtractsChemical analysisCigarette buttGC–MSLarval mortalityNicotineOviposition repellent

Identifiers

PMID40616675
PMCPMC12228669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.