Evidence map›Paper›PMID 40616674›Full record

ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025

Distal radius fracture, a predecessor to hip fracture in osteoporotic elderlies: not just a notion but a codified itinerary-Long term follow up study of 30 years (1985-2015).

Raghavendra S Kulkarni, Rachana R Kulkarni, Ranjani R Kulkarni, SriRam R Kulkarni

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Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Raghavendra S KulkarniGovernment Hospital Devgad, Kudal, Sindhudurg, Maharashtra, India. rskulkarnics@gmail.com.ORCID http://orcid.org/0000-0002-6135-2355
Rachana R KulkarniDistrict Hospital, Oros, Sindhudurg, India.ORCID https://orcid.org/0000-0003-1428-7746
Ranjani R KulkarniGoverment Polyclinic, Oros, Sindhudurg, India.ORCID https://orcid.org/0000-0002-0505-7503
SriRam R KulkarniGovernment Medical College & District Hospital, Sindhudurg, Maharashtra, India.ORCID https://orcid.org/0000-0002-1820-1578

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6 · The paper itself

Abstract

purposeThis study quantifies the long-term absolute risk of hip fracture in older individuals following distal radius fracture and explores gender-related differences in the correlation between fracture history and future fracture risk associations.

methodsA retrospective cohort study was conducted using medical records from Government Rural District hospital from 1985 to 2015, where in the author served as a full time in-house orthopedic surgeon in the same hospital during this era. All patients aged ≥ 50 years with radiographically confirmed distal radius fractures were followed for subsequent hip fractures. Cox proportional hazards regression was used to estimate hazard ratios with 95% confidence intervals, adjusting for age, sex, and their interactions.

resultsAmong 2,484 patients with distal radius fractures, 396 subsequently developed hip fractures over 30 years of follow-up. The mean interval from distal radius fracture to hip fracture ranged from 2.4 to 5.2 years across age groups (p < 0.0001). Men demonstrated higher absolute risk than women, with hazard ratios of 2.24 (95% CI 1.89-2.65) for men and 1.94 (95% CI 1.62-2.32) for women. Risk was particularly elevated in men aged 50-70 years (RH: 2.88; 95% CI 2.41-3.44).

conclusionDistal radius fractures confer substantial long-term hip fracture risk, with men showing higher absolute risk than women. These findings support using distal radius fractures as sentinel events for implementing secondary fracture prevention strategies, substantiate the notion that distal radius fracture serves as an early and sensitive indicator of male skeletal fragility.

Indexed as

Hip FracturesOsteoporotic FracturesRadius FracturesAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsSex FactorsWrist FracturesDistal radius fractureFragility fractureMale osteoporosisOsteoporosisSecondary preventionSubsequent hip fracture

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.