Evidence map›Paper›PMID 40616672›Full record

ArticleClinical oral investigations2025

Advancing 3D volumetric analysis of unilateral alveolar clefts: a study comparing methods for improved clinical precision.

Xin Wang, Xumeng Tian, Yiling Zeng, Hong He, Wenjun Yuan

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xin Wang *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, P.R. China.
Xumeng Tian *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, P.R. China.
Yiling ZengState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, P.R. China.
Hong HeState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, P.R. China.
Wenjun YuanState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, P.R. China. yuanwenjun@whu.edu.cn.ORCID http://orcid.org/0000-0002-7239-3398

Funding

Wuhan Nature Science Foundation 2024040801020358
6 · The paper itself

Abstract

objectivesThe study aims to compare methods for 3D volumetric assessment of unilateral alveolar clefts using CBCT, evaluating their accuracy and analysing clinical applicability, and to provide recommendations for improved precision in treatment planning and scientific research. MATERIALS AND

methodsTwo methods were used to assess the volumes of 20 patients with unilateral alveolar clefts. One was based on anterior nasal spine (ANS) and greater palatine foramen (GPF); while the other was based on ANS and posterior nasal spine (PNS), regarding the palatal plane (PP) as the reference plane. Reliability for the different outcome variables was analyzed with intra-class correlation (ICC) and by calculating a paired Student's t tests and Pearson's correlation coefficient.

resultsThe mean volume measured by the ANS&PNS based method (957.70 ± 174.25 mm

conclusionsThe volumetric assessment of alveolar clefts varies with the reference plane used. The method based on palatal plane offers relatively easier identification of landmarks, closely reflecting actual alveolar bone volume. CLINICAL RELEVANCE: The refined method for alveolar cleft assessment could improve treatment planning for orthodontics and alveolar bone grafting in patients with UCLP, while also supporting research on alveolar cleft morphology and its developmental mechanisms.

Indexed as

Alveolar ProcessCleft PalateCone-Beam Computed TomographyImaging, Three-DimensionalAdolescentChildFemaleHumansMaleReproducibility of Results3D imagingAlveolar bone graftingAlveolar cleftVolumetric assessment

Identifiers

PMID40616672

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