Evidence map›Paper›PMID 40616609›Full record

SynthesisEuropean journal of nutrition2025

Association between leafy vegetable consumption and incidence of metabolic syndrome and its symptoms: a systematic review of prospective cohort and randomised control trials.

Esther N Muriuki, Begum Celik, Gunter G C Kuhnle, Charlotte E Mills

Abstract readSystematic Review
In one paragraph

Synthesis in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Esther N MuriukiDepartment of Food and Nutritional Sciences, University of Reading, Whiteknights, Harry Nursten Building, Reading, RG6 6AP, UK.ORCID http://orcid.org/0009-0006-0592-9777
Begum CelikDepartment of Food and Nutritional Sciences, University of Reading, Whiteknights, Harry Nursten Building, Reading, RG6 6AP, UK.
Gunter G C KuhnleDepartment of Food and Nutritional Sciences, University of Reading, Whiteknights, Harry Nursten Building, Reading, RG6 6AP, UK.ORCID http://orcid.org/0000-0002-8081-8931
Charlotte E MillsDepartment of Food and Nutritional Sciences, University of Reading, Whiteknights, Harry Nursten Building, Reading, RG6 6AP, UK. c.e.mills@reading.ac.uk.ORCID http://orcid.org/0000-0002-8313-3700

Funding

Commonwealth Scholarship Commission Commonwealth Scholarship Commission
6 · The paper itself

Abstract

purposeMetabolic syndrome (MetS) is a combination of cardiometabolic risk factors that burden health systems worldwide. Vegetables contain substances that are essential in preventing chronic illnesses. However, the effect of leafy vegetable consumption on the incidence of MetS and its symptoms is unclear. We systematically reviewed the association between leafy vegetable consumption and the incidence of MetS and its symptoms.

methodsThe Web of Science, Scopus, and MEDLINE databases were searched for relevant publications until August 2023. Randomised control trials (RCT) and prospective cohort studies examining the effect of consumption of leafy vegetable/s on MetS or its components in healthy adults were included.

resultsTen studies (eight RCTs and two cohort studies) were included. A reduction in systolic blood pressure after intervention with leafy vegetables was observed in one RCT, but no effect on blood pressure was reported in two RCTs. One cohort study reported reduced hypertension incidence with increased leafy vegetable intake. A reduction in blood glucose was observed in three RCTs, and two RCT found no change. One cohort study reported no association between leafy vegetable consumption and the incidence of type 2 diabetes. Two RCTs found no change in blood lipids. No trials assessing leafy vegetable consumption and obesity or MetS were found.

conclusionFew studies evaluate the impact of leafy vegetable consumption on MetS and its symptoms. Beneficial effects are reported for blood glucose and blood pressure regulation, but the evidence is limited. More studies are needed to build a robust body of evidence.

Indexed as

DietMetabolic SyndromeVegetablesAdultBlood PressureFemaleHumansIncidenceMaleMiddle AgedProspective StudiesRandomized Controlled Trials as TopicLeafy vegetableMetabolic syndromeSystematic review

Identifiers

PMID40616609
PMCPMC12228594

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.