ArticleAnnals of medicine2025
Effects of daytime variation on pain intensity and analgesic requirement after cesarean section: a retrospective and prospective study.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study compared postoperative pain and analgesic requirements in women who underwent cesarean section (CS) in the morning and afternoon. SUMMARY BACKGROUND DATA: It is unclear whether there was difference in postoperative pain intensity and analgesic requirements between morning and afternoon CS.
methodsA single-center retrospective cohort study was conducted to compare postoperative analgesic requirements between women who underwent CS during 06:00-12:00 (morning group,
resultsThe frequency of analgesic requirements 24 h after CS in the afternoon group was significantly higher than morning group in the retrospective cohort. The AUC of pain NRS and analgesic consumption during 24 h after afternoon CS were significantly higher than those after morning procedures. Significantly lower pressure pain tolerance, higher postoperative serum endorphin levels and higher levels of interleukin-6 were found in the afternoon group compared to those preoperatively, but not in the morning group.
conclusionCS performed in the afternoon predicted severer postoperative pain compared to those performed in the morning, which might be associated with lower postoperative pain tolerance and more drastic responses to surgery. This finding needs to be considered in pain treatment after CS in the future. CLINICAL TRIAL NUMBER AND REGISTRY URL: ChiCTR2000039720, www.chictr.org.cn.
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