Evidence map›Paper›PMID 40616588›Full record

ArticleAnnals of medicine2025

Early detection of cognitive impairment in the general population through a digital tool targeting the prospective memory. A pilot study.

Olimpia Pino, Elisa Bertoni, Paolo Diletto, Luca Ferrari, Mauro Gaspari, Annalisa Pelosi

Abstract read
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olimpia PinoDepartment of Medicine & Surgery, University of Parma, Parma - PR, Italy.ORCID 0000-0003-3035-8401
Elisa BertoniDepartment of Medicine & Surgery, University of Parma, Parma - PR, Italy.
Paolo DilettoDepartment of Medicine & Surgery, University of Parma, Parma - PR, Italy.
Luca FerrariEnginium S.r.l. Roma, RM, Italy.
Mauro GaspariDepartment of Informatics - Science & Engineering, University of Bologna, Bologna - BO, Italy.
Annalisa PelosiDepartment of Medicine & Surgery, University of Parma, Parma - PR, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBased on Prospective Memory (PM), we developed a digitalized tool (Chrono) aimed at the detection of cognitive dysfunction. It incorporated event-based tasks signaled by focal/non-focal cues.

methodThe validation group consisted of 67 individuals (

resultsChrono score achieved an AUC = 0.813. According to sensitivity (0.83) and specificity (0.64), the optimal cut-off of 2.5 allowed discriminating between groups (

conclusionAs an exploratory study, our findings partially support the potential application of Chrono as a digital screening device for cognitive impairment.

Indexed as

Cognitive DysfunctionMemory, EpisodicAgedEarly DiagnosisFemaleHumansMaleMiddle AgedNeuropsychological TestsPilot ProjectsSensitivity and Specificitycognitive decline preventioncognitive screeningMild cognitive impairmentprospective memorytelemedicine

Identifiers

PMID40616588
PMCPMC12231265

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.