Evidence map›Paper›PMID 40616472›Full record

ArticleEuropean journal of orthodontics2025

Diagnostic accuracy of an artificial intelligence-based software in detecting supernumerary and congenitally missing teeth in panoramic radiographs.

Miltiadis A Makrygiannakis, Kostis Giannakopoulos, Argyro Kavadella, Dimitrios Paraskevis, Eleftherios G Kaklamanos

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Article in European journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miltiadis A MakrygiannakisSchool of Dentistry, European University Cyprus, 6 Diogenous str., Nicosia 2404, Cyprus.ORCID 0000-0003-2855-8623
Kostis GiannakopoulosSchool of Dentistry, European University Cyprus, 6 Diogenous str., Nicosia 2404, Cyprus.ORCID 0000-0001-7008-7306
Argyro KavadellaSchool of Dentistry, European University Cyprus, 6 Diogenous str., Nicosia 2404, Cyprus.
Dimitrios ParaskevisSchool of Dentistry, European University Cyprus, 6 Diogenous str., Nicosia 2404, Cyprus.ORCID 0000-0001-6167-7152
Eleftherios G KaklamanosSchool of Dentistry, European University Cyprus, 6 Diogenous str., Nicosia 2404, Cyprus.ORCID 0000-0002-0513-5110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesRecent advances in AI have enabled its application in dentistry. This study assessed the diagnostic accuracy of an AI-based model (Diagnocat™) in detecting congenitally missing and supernumerary teeth on panoramic radiographs. MATERIALS/

methodsThree groups of 50 orthopantomograms each-control, congenitally missing, and supernumerary teeth-were evaluated by two human observers and Diagnocat™. Diagnostic performance was compared using the Wilcoxon Signed Rank and McNemar's tests. Agreement was measured using Cohen's Kappa, and diagnostic metrics (sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV)) were computed using IBM SPSS 29.0.

resultsFor congenitally missing teeth, Cohen's Kappa indicated strong agreement (0.91); however, significant differences were found in the diagnostic performance (p < 0.01). The model exhibited 84.7% sensitivity, 100.0% specificity, 100.0% PPV, and 99.4% NPV. For supernumerary teeth, the agreement was moderate (Kappa = 0.60), with significant differences in the diagnostic performance (p < 0.001). Sensitivity was 43.9%, while specificity, PPV, and NPV were 100.0%, 100.0%, and 98.9%, respectively. LIMITATIONS: Using convenience sampling and a retrospective design may affect generalizability and applicability. CONCLUSIONS/IMPLICATIONS: Although the AI-based model shows promise, it is not yet able to replace human assessment as the standard for detecting missing and supernumerary teeth in panoramic radiographs.

Indexed as

AnodontiaArtificial IntelligenceRadiography, PanoramicSoftwareTooth, SupernumeraryAdolescentAdultFemaleHumansMalePredictive Value of TestsSensitivity and SpecificityYoung Adultartificial intelligencediagnocat™hypodontiasupernumerary teeth

Identifiers

PMID40616472
PMCPMC12228091

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.