Evidence map›Paper›PMID 40616364›Full record

ReviewWiley interdisciplinary reviews. Cognitive science

Digital Screening for Early Identification of Cognitive Impairment: A Narrative Review.

Ester Cornacchia, Aurora Bonvino, Giorgia Francesca Scaramuzzi, Daphne Gasparre, Roberta Simeoli, Davide Marocco, Paolo Taurisano

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Cognitive science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Cognitive Trajectories After Hospitalization for COVID-19: A 36-Month Longitudinal Study.The Journal of neuropsychiatry and clinical neurosciences · 2026
    Article
  3. Validation of a Web-Based Digit Symbol Substitution Task for Detection of Mild Cognitive Impairment in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ester CornacchiaDepartment of Translational Biomedicine and Neuroscience - DiBraiN, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0009-0002-0421-3348
Aurora BonvinoDepartment of Translational Biomedicine and Neuroscience - DiBraiN, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0000-0001-8772-5992
Giorgia Francesca ScaramuzziDepartment of Translational Biomedicine and Neuroscience - DiBraiN, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0009-0004-9518-9252
Daphne GasparreDepartment of Translational Biomedicine and Neuroscience - DiBraiN, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0009-0001-0443-2527
Roberta SimeoliDepartment of Humanistic Studies, University of Naples Federico II, Naples, Italy.ORCID https://orcid.org/0000-0001-7564-6816
Davide MaroccoDepartment of Humanistic Studies, University of Naples Federico II, Naples, Italy.ORCID https://orcid.org/0000-0001-5185-1313
Paolo TaurisanoDepartment of Translational Biomedicine and Neuroscience - DiBraiN, University of Bari Aldo Moro, Bari, Italy.ORCID https://orcid.org/0000-0001-6140-9326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As longevity increases, cognitive decline in older adults has become a growing concern. Consequently, an increasing interest in the potential of digital tools (e.g., serious games (SG) and virtual reality (VR)) for early screening of Mild Cognitive Impairment (MCI) is emerging. Traditional cognitive assessments like the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) are widely used but have limitations related to cultural bias and manual scoring, while their digital adaptations, such as MOCA-CC, maintain diagnostic accuracy while offering remote administration and automated scoring. Innovative tools, such as the Virtual Super Market (VSM) test and Panoramix Suite, instead, assess cognitive domains like memory, attention, and executive function while promoting engagement and preserving ecological validity, making assessments more reflective of real-world tasks. Several studies show that these tools exhibit strong diagnostic performance, with sensitivity and specificity often exceeding 80%. However, although digital tools offer advantages in accessibility and user engagement, challenges remain concerning technological literacy, data privacy, and long-term validation. Future research should focus on validating these tools across diverse populations and exploring hybrid models that combine traditional and digital assessments, as digital tools show promise in transforming cognitive screening and enabling earlier interventions for cognitive decline. This article is categorized under: Psychology > Development and Aging Neuroscience > Cognition.

Indexed as

Cognitive DysfunctionEarly DiagnosisHumansMass ScreeningMental Status and Dementia TestsNeuropsychological Testscognitive screeningdiagnostic accuracydigital toolsneurocognitive disorders

Identifiers

PMID40616364
PMCPMC12228087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.