Evidence map›Paper›PMID 40616193›Full record

ArticlePneumonia (Nathan Qld.)2025

Organizing pneumonia in hospitalized COVID-19 patients: risk factors and long-term outcomes.

Sandra Cuerpo, Fernanda Hernandez-Gonzalez, Mariana Benegas, Nuria Albacar, Alejandra Lopez-Giraldo, Inés Cobo, Samara Suarez, Verónica Torres, Adelaido Salazar, Nestor Soler and 20 more

Abstract read
In one paragraph

Article in Pneumonia (Nathan Qld.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Scar wars: the viral menace.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  7. Persistent COVID-19 Pneumonia in a Patient on Rituximab.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Sandra CuerpoServei d'Urgències, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Fernanda Hernandez-GonzalezServei de Pneumologia, Institut Clinic Respiratori, Hospital Clínic, C/ Villarroel 170, Barcelona, 08036, Spain.
Mariana BenegasServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Nuria AlbacarServei de Pneumologia, Institut Clinic Respiratori, Hospital Clínic, C/ Villarroel 170, Barcelona, 08036, Spain.
Alejandra Lopez-GiraldoServei de Pneumologia, Hospital San Joan de Deu, Sant Boi de Llobregat, Spain.
Inés CoboServei de Pneumologia, Institut Clinic Respiratori, Hospital Clínic, C/ Villarroel 170, Barcelona, 08036, Spain.
Samara SuarezServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Verónica TorresServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Adelaido SalazarServei de Medicina Interna, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Nestor SolerServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
María Noboa-SevillaServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Alejandro Frino-GarcíaServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Nancy Pérez-RodasServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Joel FrancesquiServei de Pneumologia, Hospital de Granollers, Barcelona, Spain.
Xavier Alsina-RestoyServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Ana María Muñoz FernándezServei de Pneumologia, Hospital de Vic, Barcelona, Spain.
Nuria RogerServei de Pneumologia, Hospital de Vic, Barcelona, Spain.
Sergio PrietoServei de Medicina Interna, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Alexandru VlageaServei d'Immunologia, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Estibaliz RuizServei d'Immunologia, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Rosa FanerInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Joan Albert BarberàServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Alex SorianoServei de Malalties Infeccioses, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Joan Ramon BadiaServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
María Molina-MolinaCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain.
Oriol SibilaServei de Radiologia, Centre Diagnostic per la Imatge, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Marcelo SánchezServei de Pneumologia, Hospital San Joan de Deu, Sant Boi de Llobregat, Spain.
Alvar Agustí *Servei de Pneumologia, Institut Clinic Respiratori, Hospital Clínic, C/ Villarroel 170, Barcelona, 08036, Spain.
Judith Garcia-Aymerich *ISGlobal, Barcelona, Spain.
Jacobo Sellares *Servei de Pneumologia, Institut Clinic Respiratori, Hospital Clínic, C/ Villarroel 170, Barcelona, 08036, Spain. sellares@clinic.cat.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome patients develop post-COVID-19 organizing pneumonia (OP) that is responsive to corticosteroid treatment. This multicenter, case-control study of patients hospitalized for COVID-19 sought to determine the prevalence, risk factors, radiological outcomes, and evolution after treatment.

methodsWe included 153 consecutive patients with OP and 140 without OP who required hospitalization because of COVID-19 from February to April 2020. OP patients were followed up for 12 months, with visits at 1, 3, 6, and 12 months after hospital discharge.

resultsRisk factors for OP at hospital admission were advanced age, previous respiratory disease, and elevated C-reactive protein levels. Follow-up computed thoracic (CT) scans performed one year after admission showed progressive improvement in radiological involvement; however, up to 57% of patients with OP remained with fibrotic-like changes. Multivariate analysis showed a significant association of fibrotic pattern with older age, high dose of corticosteroids, and extensive parenchymal lung involvement on admission CT scans.

conclusionsFollowing COVID-19 OP, fibrotic-like changes may persist over the long term. Higher dose of corticosteroids does not seem to be associated with a better prognosis.

Indexed as

CorticosteroidsCOVID-19Organizing pneumonia

Identifiers

PMID40616193
PMCPMC12228227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.