Evidence map›Paper›PMID 40616143›Full record

ArticleBMC nutrition2025

To smoothie or not to smoothie? A mixed-method approach of nutrition pilot intervention among individuals in opioid agonist treatment.

Siv-Elin Leirvaag Carlsen, Einar Furulund, Elaheh Javadi Arjmand, Karl Trygve Druckrey Fiskaaen, Jørn Henrik Vold, Tesfaye Madebo, Torgeir Gilje Lid, Lars T Fadnes, ATLAS4LAR and FruktBAR study group

Abstract read
In one paragraph

Article in BMC nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siv-Elin Leirvaag CarlsenBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway. leis@helse-bergen.no.
Einar FurulundBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Elaheh Javadi ArjmandBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Karl Trygve Druckrey FiskaaenBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Jørn Henrik VoldBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Tesfaye MadeboBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
Torgeir Gilje LidCentre for Alcohol and Drug Research, Stavanger University Hospital, Stavanger, Norway.
Lars T FadnesBergen Addiction Research, Department of Addiction Medicine, Haukeland University Hospital, Bergen, Norway.
ATLAS4LAR and FruktBAR study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with substance dependence typically have unhealthy diets and low degree of nutritional awareness. They frequently face nutritional deficiencies in both micro- and macronutrients, which can have a significant impact on their overall health. Incorporating more fruits and vegetables into their diet has been associated with reduction in diseases such as cardiovascular diseases and certain cancers. This mixed-method study aims to gain insight into participants' experience and feasibility of a pilot intervention of receiving 250 ml/day of fruit smoothies for a six-week period.

methodsIndividuals undergoing opioid agonist treatment in Bergen and Stavanger, Norway, were recruited for this multi-center pilot study. This study had a pre- and post-intervention design where an explanatory sequential design was employed, integrating qualitative methods to delve into patients' experiences and perspectives. In addition, psychological distress (Hopkins Symptom Checklist (SCL-10), fatigue (three-item Fatigue Severity Scale (FSS-3)), and nutrition status (folic acid) were measured.

resultsTwenty-four individuals with a mean age of 47 years (standard deviation: 8.6) participated. They expressed feeling more energetic and being more active, and some reported eating more meals than before and adding new food items to their diet. Oral health was a barrier to eating more vegetables and fruits while smoothies, on the other hand, were easy to consume even with poor dental status. There were no clear indications of changes in psychological distress (pre-test: 2.09 vs. post-test: 2.08) or fatigue (post-test: 4.19 vs. post-test: 4.43). Folic acid levels increased from 15.3 nmol/L at baseline to 17.0 nmol/L after the intervention.

conclusionReceiving fruit smoothies seems to have several benefits for patients undergoing opioid agonist treatment, including helping them reflect on their health and diet and expressing more awareness about nutrition. Providing smoothies alongside patients' opioid agonist treatment was seen as feasible and can be a door opener for clinicians to discuss nutritional issues in this population. To evaluate the effectiveness, a sufficiently powered randomized controlled trial is needed.

Indexed as

Mental and somatic healthMixed- methodMulticenter pilot studyNutritionOpioid agonist treatment

Identifiers

PMID40616143
PMCPMC12228150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.