SynthesisMalaria journal2025
Prevalence and determinants of zoonotic malaria in the Greater Mekong Subregion (GMS) and Malaysia: systematic review and meta-analysis.
Synthesis in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Synthesis of qualitative evidence on community experiences and perceptions of Plasmodium knowlesi malaria and factors influencing prevention and healthcare-seeking behaviours in Malaysia.Malaria journal · 2026Review
- Do natural or synthetic excito-repellents work better? A study on coastal malaria vectorPeerJ · 2026Article
- Epidemiology of malaria and leishmaniasis in Thailand (2004-2025): A systematic review.Current research in parasitology & vector-borne diseases · 2026Review
- Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundZoonotic malaria is a growing public health concern in Southeast Asia, with Malaysia and Thailand accounting for 95.2% of the 3290 global cases reported in 2023. It is caused by Plasmodium species primarily adapted to long- and pig-tailed macaques, transmitted to humans via certain Anopheles mosquitoes. This meta-analysis quantifies its prevalence and risk factors in the Greater Mekong Subregion and Malaysia.
methodsThis meta-analysis was conducted following the PRISMA (Preferred Reporting Items for Systematic) guidelines. A comprehensive literature search was conducted in PubMed and Scopus databases (2000-2024) to identify studies on zoonotic malaria infection in humans and monkeys. Backward search was done using Google Scholar. Inclusion criteria were defined using the CoCoPop (Condition, Context, and Population) framework. Two reviewers independently extracted data, and study quality was assessed using appropriate risk-of-bias tools. A random-effects meta-analysis was conducted using the metafor package in R programme, with heterogeneity assessed via I
resultsThe overall pooled prevalence of malaria infection was 8.6% in humans and 35.0% in monkeys. The pooled prevalence was higher in Malaysia (22.8%) than GMS (1.2%). In GMS, Myanmar with a pooled prevalence of 4.9% contributes a higher burden of human zoonotic malaria than Thailand (1.8%). Significantly high heterogeneity between studies was recorded for both human (I
conclusionsThis study contributes to the understanding of the transmission complexities of zoonotic malaria in the GMS countries and Malaysia, highlighting critical knowledge gaps and the need for a multidisciplinary approach to managing its further spread.
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