SynthesisBMC musculoskeletal disorders2025
Clinical outcomes of restricted kinematic alignment versus mechanical alignment in total knee arthroplasty: a meta-analysis of randomized controlled trials.
Synthesis in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Unicompartmental knee arthroplasty and total knee arthroplasty in patients with 15 or more degrees of varus deformity: age- and gender-matched comparative study of radiographic and clinical outcomes.Archives of orthopaedic and trauma surgery · 2026Article
- Coronal plane alignment changes do not affect in vivo kinematics for robotically performed total knee arthroplasty.Journal of experimental orthopaedics · 2026Article
- Functional alignment preserves the native Coronal Plane Alignment of the Knee phenotype while improving early clinical outcomes after robotic-assisted total knee arthroplasty.Orthopedic reviews · 2026Article
- Kinematic alignment in total knee replacement successfully restores the native knee phenotype in the short term.Journal of experimental orthopaedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundRestricted Kinematic Alignment (rKA) is a well-established technique for total knee arthroplasty (TKA) that aims to approximate natural knee motion within defined safety boundaries. This meta-analysis aims to evaluate the clinical efficacy of rKA compared to mechanical alignment (MA) in TKA.
methodA comprehensive search was conducted in the PubMed, Embase, Web of Science, and Cochrane Library databases for randomized controlled trials (RCTs) published from the inception of these databases until December 6, 2024. RCTs assessing the clinical efficacy of rKA and MA in TKA were included. A total of six RCTs were analyzed.
resultsA total of six RCTs involving 444 patients were included in the analysis. The meta-analysis revealed that the Knee Society Score (KSS) and McMaster Universities Osteoarthritis Index (WOMAC) scores were significantly higher in the rKA group compared to the MA group. However, no significant differences were found between the rKA and MA groups in terms of the Oxford Knee Score (OKS), Knee Injury and Osteoarthritis Outcome Score (KOOS), Forgotten Joint Score (FJS), hip-knee-ankle angle (HKA), and lateral distal femoral angle (LDFA). Additionally, the postoperative revision rate in the rKA group was not significantly different from that in the MA group.
conclusionThis study suggests that rKA provides better functional outcomes in TKA compared to MA, particularly in terms of WOMAC score and KSS. CLINICAL TRIAL NUMBER: Not applicable.
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