Evidence map›Paper›PMID 40615942›Full record

ArticleBMC plant biology2025

Genome-wide identification of wheat Ubiquitin-conjugating enzyme gene family and its role in wheat powdery mildew disease resistance.

Ping Hu, Lu Zhang, Jun Xu, Yueming Ren, Mengfei Wang, Wanglong Luo, Kaige Zhou, Xinjie Zhu, Zhiyuan Liu, Haiyan Hu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ping HuCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China. huping@hist.edu.cn.
Lu ZhangCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China.
Jun XuCollege of Horticulture and Landscape Architecture, Henan Institute of Science and Technology, Xinxiang, China.
Yueming RenCollege of Life Science, Henan Agricultural University, Zhengzhou, China.
Mengfei WangCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China.
Wanglong LuoCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China.
Kaige ZhouCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China.
Xinjie ZhuCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China.
Zhiyuan LiuCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China.
Haiyan HuCollege of Agriculture/Henan Engineering Research Centre of Crop Genome Editing, Henan Institute of Science and Technology, Xinxiang, China. haiyanhuhhy@126.com.
Chengwei LiCollege of Life Science, Henan Agricultural University, Zhengzhou, China. lcw@henau.edu.cn.

Funding

Basic Research Special Project of Key Research Projects in Higher Education Institutions of Henan Province No. 24ZX013National Natural Science Foundation of China No. 31901538
6 · The paper itself

Abstract

Ubiquitin-conjugating enzyme (UBC) E2 is a critical component of the ubiquitination process. It interacts with the RING domain of E3 ligases through its UBC domain, enables specific identification of substrate proteins, thereby plays a pivotal role in plant growth and development. In this study, the number, gene structure, and evolutionary relationships of UBC genes in wheat and Arabidopsis thaliana were analyzed at a whole-genome level. Furthermore, the roles of TaUBC genes in wheat resistance to powdery mildew were investigated. A total of 180 UBC genes were identified in wheat and categorized into 15 Classes through phylogenetic analysis. Quantitative real-time PCR analysis revealed significant expression changes of TaUBC1A-5, TaUBC1A-6, TaUBC3A-5, TaUBC3B-14, TaUBC5A-2, TaUBC6A-2, and TaUBC7A-2 after the powdery mildew infection, compared to the 0-h time point. Virus-induced gene silencing experiments demonstrated that TaUBC3A-5 positively regulates wheat resistance to powdery mildew, whereas TaUBC3B-14 acts as a negative regulator. These findings provide valuable insights into the function of the UBC gene family in wheat and offer support for development of new disease-resistant wheat germplasm using UBC genes.

Indexed as

AscomycotaDisease ResistancePlant DiseasesPlant ProteinsTriticumUbiquitin-Conjugating EnzymesArabidopsisGene Expression Regulation, PlantGenes, PlantMultigene FamilyPhylogenyPlant ProteinsUbiquitin-Conjugating EnzymesGene expressionPowdery mildewUBC gene familyVirus-induced gene silencingWheat

Identifiers

PMID40615942
PMCPMC12231674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.