Trial reportBiomedical engineering online2025
Combined therapy with contralateral controlled functional electrical stimulation and transcranial direct current stimulation for early post-stroke hand dysfunction.
Trial report in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Network meta-analysis of different electrical stimulation therapies for lower limb functional rehabilitation in stroke patients.Frontiers in neurology · 2025Pooled it
- Effects of Transcranial Direct Current Stimulation Combined with Peripheral Electrical Stimulation on Upper Limb Function Recovery in Stroke: A Systematic Review and Meta-Analysis.Brain sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the clinical efficacy of contralateral controlled functional electrical stimulation (CCFES) combined with transcranial direct current stimulation (tDCS) in the treatment of patients with early post-stroke hand dysfunction.
methodsNinety patients with definitively diagnosed early post-stroke hand dysfunction were selected and divided into the control group (30 cases), experimental group 1 (EG1; 30 cases) and experimental group 2 (EG2; 30 cases) according to the random number table method. The control group received traditional therapy; experimental group 1 received tDCS in addition to standard care; experimental group 2 received both tDCS and CCFES in addition to standard treatments. Before and after treatment, all three groups were evaluated using the Fugl-Meyer assessment for upper extremity (FMA-UE), the functional test for the hemiplegic upper extremity-Hong Kong version (FTHUE-HK), the Modified Barthel Index (MBI), the Brunnstrom stages of hand, the Motor Assessment Scale (MAS) and surface electromyography (sEMG).
resultsBefore treatment, there were no significant differences in baseline characteristics among the three groups (P > 0.05). After treatment, significant improvements were observed in FMA-UE score, FTHUE-HK grading, MBI score, Brunnstrom hand staging, MAS score and sEMG compared with pre-treatment values (P < 0.05). Specifically, EG1 showed greater improvements than the control group (P < 0.05), whereas EG2 demonstrated better outcomes than both EG1 and the control group (P < 0.05).
conclusionsContralateral controlled functional electrical stimulation combined with tDCS substantially improves hand function in patients with early stage stroke, with better outcomes than tDCS therapy alone.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.