Association of preoperative health status with risk of complications after primary total hip arthroplasty: how useful are the measures self-rated health, ASA classification and comorbidity count?

Alice Bonnefoy-Mazure, Donia Dellagiovanna, Christophe Barea, Didier Hannouche, Anne Lübbeke

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Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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1 citing paper in PubMed.

Precise perioperative assessment and anesthesia strategy for painless gastrointestinal endoscopy in high-risk cardiovascular disease patients.iScience · 2026
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5 · Who and what money

Authors and funding

5 authors.

Alice Bonnefoy-MazureWilly Taillard Laboratory of Kinesiology, Faculty of Medicine, Geneva University Hospitals, University of Geneva, 4 Rue Gabrielle-Perret-Gentil, Geneva 14, CH-1211, Switzerland. alice.bonnefoymazure@hcuge.ch.

Donia DellagiovannaFaculty of Medicine, University of Geneva, Geneva, Switzerland.

Christophe BareaFaculty of Medicine, University of Geneva, Geneva, Switzerland.

Didier HannoucheFaculty of Medicine, University of Geneva, Geneva, Switzerland.

Anne LübbekeFaculty of Medicine, University of Geneva, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplications after surgery can be predicted using ASA classification or comorbidity count. No study has assessed the measure self-rated health (SRH) yet. Our objective was to assess the association between SRH, ASA and comorbidity count and medical complications during hospitalization, and death and all-cause revision within 5years.

methodsA prospective cohort study of primary elective total hip arthroplasties (THA) was conducted 2002-2019 including information on preoperative general health measured with SRH, comorbidity count and ASA grade. For medical complications, proportions of events per category of health measure were calculated. Risk of all-cause revision and mortality was assessed in the first five years after surgery using reverse Kaplan-Meier and Cox regression analyses.

resultsOverall, 3906 patients were included (mean age 69years). The risks of experiencing at least one medical complication and a severe medical complication during hospitalization were 27.2% and 1%, increasing with decreasing health status. Cumulative 5-year risk of dying was 9.5% (95%CI 8.5-10.6), increasing with decreasing health status. ASA grade 3-4 was most strongly associated with death (hazard ratio (HR) 5.0, 95%CI 2.3-10-8) compared to ASA grade 1. Patients with poor SRH or ≥ 4 comorbidities had a 3 times higher risk of dying. Cumulative 5-year risk of revision overall was 3.1% (95%CI 2.6-3.7), increasing with decreasing health status. The association was only significant in the first 3 months postoperative. For comorbidity count the adjusted HR was 3.6 (95%CI 1.9-6.8), and for ASA 3-4 h was 3.3 (95%CI 1.8-6.1).

conclusionSRH, ASA classification and comorbidity count showed increasing risks of medical complications and death with decreasing health status. ASA was most strongly associated with death. Regarding revision both comorbidity count and ASA performed well. SRH was associated with medical complications and death independent of the effect of ASA score or number of comorbidities indicating differences between health status measurements with respect to the underlying mechanisms.

Indexed as

Arthroplasty, Replacement, HipDiagnostic Self EvaluationHealth StatusPostoperative ComplicationsSelf ReportAgedAged, 80 and overComorbidityFemaleHumansMaleMiddle AgedPreoperative PeriodProspective StudiesReoperationRisk FactorsASA classificationComorbidity countPrimary total hip arthroplastySelf-rated health

Identifiers

PMID40615858

DOI10.1186/s12891-025-08745-2

PMCPMC12228163

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