ArticleBMC cardiovascular disorders2025
Evaluation of the volume and function of the right atrial appendage using computed tomography.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Novel technique for leadless pacemaker implantation in the small right atrial appendage: a case report.European heart journal. Case reports · 2026Article
- Calculation of Ejection Fraction Using Cardiac Computed Tomography: Clinical Evolution, Reliability, and Technological Challenges-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
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Abstract
objectiveTo assess the volume and function of the right atrial appendage (RAA) in patients with sinus rhythm using 256-slice spiral computed tomography (CT) angiography.
methodsA total of 60 patients with normal cardiac CT imaging features were enrolled in this retrospective study. The raw imaging data were used to reconstruct 3D images, which were analyzed to measure the volume of the RAA and right atrium (RA) throughout the cardiac cycle, and to obtain the maximum and minimum volume of the RAA and RA (RAAVmax, RAAVmin and RAVmax, RAVmin). Additionally, the RAA ejection volume (RAAEV), RAA ejection fraction (RAAEF), RA ejection volume (RAEV), and ejection fraction (RAEF) were calculated. Independent sample t-tests were used to analyze the data of the RAA and RA between male and female groups. Pearson correlation analysis was used to analyze the correlation between RAA parameters, RA parameters and basic physiological parameters of the human body.
resultsThe volumes of the RAA and RA constantly changed throughout the cardiac cycle, characterized by similar curves and two emptying phases. During 65–85% of the cardiac cycle, the volume of RAA exhibited a minimal fluctuation, indicating a resting state. Male patients had significantly (P < 0.05) greater values than female in the RAAVmax, RAAEV, RAVmax, and RAVmin(P = 0.003, P = 0.001, P = 0.031 and P = 0.025, respectively). RAAVmax correlated with the patient’s weight, body surface area (BSA), RAVmax, RAVmin and RAAVmin (r = 0.434 P = 0.001, r = 0.363 P = 0.004, r = 0.331 P = 0.010, r = 0.352 P = 0.006 and r = 0.858 P = 1.9485E-18, respectively), but did not significantly correlated with height. RAAVmin positively correlated with the weight, BSA, RAVmax, and RAVmin (r = 0.434 P = 0.011, r = 0.363 P = 0.035, r = 0.331 P = 0.006, and r = 0.352 P = 0.000368, respectively), but did not significantly correlated with height. Additionally, RAAEV correlated with weight, BSA, RAAVmax, and RAAVmin (r = 0.426 P = 0.001, r = 0.356 P = 0.005, r = 0.885, P = 5.9452E-21 and r = 0.521 P = 0.00020, respectively). RAAEF showed a negative correlation with both RAAVmin and RAVmin (r=–0.478 P = 0.000112 and r=–0.289 P = 0.025, respectively).
conclusionCT angiography with multi-phase three-dimensional volume reconstruction is very helpful in evaluating the volume and function of RAA, providing an important guidance for diagnosis and treatment of cardiac diseases.
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