Evidence map›Paper›PMID 40615811›Full record

ArticleBMC nephrology2025

Perspectives of adult advanced pre-dialysis chronic kidney disease patients about kidney replacement therapy in three referral hospitals in Rwanda.

Gloria Shumbusho, Darlene L Nyenyeri, Jules Kabahizi, Darius Uwiragiye, Oswald Habyarimana, Gad Binayisa, Alice Nyirangirimana, Emile Twagirumukiza, Kara L Neil, Negussie Deyessa and 6 more

Abstract readMulticenter Study
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gloria ShumbushoKing Faisal Hospital Rwanda, Kigali City, Rwanda. glorishu@gmail.com.
Darlene L NyenyeriKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Jules KabahiziRwanda Military Hospital, Kigali, Rwanda.
Darius UwiragiyeKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Oswald HabyarimanaKigali University Teaching Hospital, Kigali City, Rwanda.
Gad BinayisaKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Alice NyirangirimanaKigali University Teaching Hospital, Kigali City, Rwanda.
Emile TwagirumukizaKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Kara L NeilKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Negussie DeyessaAfrica Health Sciences University, Kigali City, Rwanda.
Alan LeichtmanSchool of Medicine, University of Michigan, Ann Arbor, MI, USA.
Janvier MurayireKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Erhard DufatanyeKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Gerard NkundimanaKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Emile SeberaKing Faisal Hospital Rwanda, Kigali City, Rwanda.
Ahmed M ElbashaKing Faisal Hospital Rwanda, Kigali City, Rwanda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited access to kidney replacement therapy (KRT) in Rwanda results from financial constraints, geographic challenges, a shortage of nephrologists and equipment, as well as low public awareness. We aimed to identify the factors contributing to patients' decisions regarding KRT and understand their perspectives on KRT, including their understanding, attitudes, and expectations.

methodsA cross-sectional mixed method design was conducted between May 2023 and March 2024, involving 180 chronic kidney disease (CKD) adult patients (> 18 years old) with an estimated GFR < 30 ml/min/1.73 m². It was conducted at outpatient nephrology clinics at King Faisal Hospital-Rwanda, Kigali University Teaching Hospital, and Rwanda Military Hospital. Quantitative data from hospital registries were analyzed in Stata SE 17.0, employing descriptive, bivariate, and multinomial techniques to determine factors associated with KRT modality choice. Additionally, 15 participants were conveniently selected for interviews and analysis of transcripted records were conducted using ATLAS.ti.

resultsThe mean age was 52.2 [SD = 13.9] years, with a higher representation of males. Two-thirds of the participants had end-stage kidney disease (kidney failure) with a mean eGFR of 14.64 ml/min/1.73m

conclusionThe findings revealed that prior nephrology visits significantly influenced treatment choices. Healthcare providers served as key information sources, while financial constraints and limited knowledge of CKD progression and management emerged as major barriers to optimal care. The findings indicate the need for establishing pre-dialysis clinics for improved information access and patient support. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Health Knowledge, Attitudes, PracticeRenal Insufficiency, ChronicRenal Replacement TherapyAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedReferral and ConsultationRwandaChronic kidney diseaseDialysisKidney transplantationRwanda

Identifiers

PMID40615811
PMCPMC12231732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.